297143-31-8

Basic information

• Product Name: 2-Azabicyclo[2.2.1]heptane-3-carboxylicacid,methylester,(1S,3R,4R)-(9CI)
• Synonyms: 2-Azabicyclo[2.2.1]heptane-3-carboxylicacid,methylester,(1S,3R,4R)-(9CI);(1S, 3R, 4R)-2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid methyl ester
• CAS NO: 297143-31-8
• Molecular Formula: C₈H₁₃NO₂
• Molecular Weight: 155.19
• Product Categories: CARBOXYLICESTER;GLYCINESCAFFOLD;PYRROLE
• Mol File: 297143-31-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Azabicyclo[2.2.1]heptane-3-carboxylicacid,methylester,(1S,3R,4R)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azabicyclo[2.2.1]heptane-3-carboxylicacid,methylester,(1S,3R,4R)-(9CI)(297143-31-8)
• EPA Substance Registry System: 2-Azabicyclo[2.2.1]heptane-3-carboxylicacid,methylester,(1S,3R,4R)-(9CI)(297143-31-8)

Safety Data

• Hazardous Substances Data: 297143-31-8(Hazardous Substances Data)

Usage

Stereochemistry

(1S,3R,4R)
Potential applications in drug development and bioactive molecule synthesis

Upstream product

• 130195-74-3 (1R,3R,4S)-2-[(1S)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylic acid methyl ester 
• 542-92-7 cyclopenta-1,3-diene 

Downstream Products

• 251302-01-9 (1S,3R,4R)-2-benzyl-2-azabicyclo[2.2.1]heptane-3-carboxylic acid methyl ester 
• 553645-77-5 (1S,3R,4R)-3-benzylsulfanylmethyl-2-azabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester 
• 553645-76-4 (1S,3R,4R)-3-(toluene-4-sulfonyloxymethyl)-2-azabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester 
• 297143-30-7 (1S,3R,4R)-2-(p-tert-butylphenylsulphonyl)-2-aza-bicyclo[2.2.1]heptane-3-caboxylic acid 
• 251302-03-1 (1S,3S,4R)-2-benzyl-2-azabicyclo[2.2.1]heptane-3-methyl-3-carboxylic acid methyl ester 
• 251302-09-7 C₅H₇CO₂CH₃NC₆H₅C₂H₄C₆H₅CHO 
• 297143-32-9 (1S,3R,4R)-2-(4-tert-butylphenylsulfonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic acid methyl ester 

Relevant articles and documents

MACROCYCLIC INHIBITORS OF PEPTIDYLARGININE DEIMINASES

The present disclosure relates to novel compounds for use in therapeutic treatement of a disease associated with peptidylarginine deiminases (PADs), such as peptidylarginine deiminase type 4 (PAD4). The present disclosure also relates to processes and intermediates for the preparation of such compounds, methods of using such compounds and pharmaceutical compositions comprising the compounds described herein.

Highly diastereoselective reaction of 2-azanorbornyl enolates with electrophiles

(matrix presented). A highly diastereoselective reaction of 2-azanorbornyl enolates with electrophiles has been studied. Deprotonation of 4 with LDA at low temperature affords the corresponding exocyclic lithium enolate 5, which reacts with different elec