55368-76-8Relevant academic research and scientific papers
Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles
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Page/Page column 22-23; 30, (2010/11/24)
Novel dicationic 3,5-diphenylisoxazole compounds are described. Synthetic routes to these novel compounds are provided. Several of the compounds displayed in vitro activity versus Trypanosoma brucei brucei and Plasmodium falciparum comparable to that of furamidine. A majority of the novel compounds also were less toxic to VERO cells than furamidine.
