5538-00-1

Upstream product

• 15732-75-9 3-benzoyl-2-methylenepropionic acid 
• 5537-96-2 3-Oxo-3-phenyl-propan-tricarbonsaeure-(1,1,1)-trimethylester 
• 3775-32-4 2-methylidenetrimethylene carbonate 
• 100-52-7 benzaldehyde 
• 3513-81-3 2-(Hydroxymethyl)allyl alcohol 
• 70-11-1 α-bromoacetophenone 

Relevant academic research and scientific papers

Palladium-catalyzed carbonyl allylation of aldehydes by allylic cyclic carbonates

Palladium(0)-catalyzed allylation of aldehydes by allylic cyclic carbonates with SnCl2 proceeded smoothly tto afford 1,3-diols with high diastereocontrol. For the exomethylene cyclic carbonate, allylation with aldehydes furnished 1,4-diols or 1

Diastereoselective synthesis of 2,6-disubstituted 4-(Dimethoxymethyl)tetra- hydropyrans using TMSOTf-promoted prins-pinacol cyclization

We have described a highly diastereoselective synthesis of 2,6-disubstituted 4-(dimethoxymethyl)tetrahydropyrans via TMSOTf-promoted Prins-pinacol reaction of methylene diol with acetals. This reaction provides an efficient procedure to synthesize functionalized tetrahydropyrans containing an acetal group at the C4 position with all-cis 2,4,6 relative configuration.

Palladium-catalysed carbonyl allylation by 2-methylenepropane-1,3-diol

2-Methylenepropane-1,3-diol first allylates an aldehyde exclusively at the allylic alcohol moiety at room temperature and then, at 50°C, allylates another aldehyde also at the allylic alcohol moiety, in the presence of a catalytic amount of PdCl2(PhCN)2 with tin(II) chloride.

Tosylated lithium 2-(lithiomethyl)-2-propen-1-olate: A γ-alkoxide allyl sulfone anion in organic synthesis

Dilithiated 2-(tosylmethyl)-2-propen-1-ol (6) functioned as a nucleophile at the α-position of the allylic anion in reactions with deuterium oxide, alkyl halides, and aldehydes, and in conjugate additions to α,β-unsaturated carbonyl compounds. With nitro-