5538-00-1

Basic information

• Product Name: (+/-)-2-methylene-4-phenyl-1,4-butanediol
• Synonyms: (+/-)-2-methylene-4-phenyl-1,4-butanediol
• CAS NO: 5538-00-1
• Molecular Weight: 178.231
• Mol File: 5538-00-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (+/-)-2-methylene-4-phenyl-1,4-butanediol(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-2-methylene-4-phenyl-1,4-butanediol(5538-00-1)
• EPA Substance Registry System: (+/-)-2-methylene-4-phenyl-1,4-butanediol(5538-00-1)

Safety Data

• Hazardous Substances Data: 5538-00-1(Hazardous Substances Data)

Upstream product

• 3513-81-3 2-(Hydroxymethyl)allyl alcohol 
• 100-52-7 benzaldehyde 
• 70-11-1 α-bromoacetophenone 
• 5537-96-2 3-Oxo-3-phenyl-propan-tricarbonsaeure-(1,1,1)-trimethylester 
• 15732-75-9 3-benzoyl-2-methylenepropionic acid 
• 3775-32-4 2-methylidenetrimethylene carbonate 

Relevant articles and documents

Palladium-catalyzed carbonyl allylation of aldehydes by allylic cyclic carbonates

Palladium(0)-catalyzed allylation of aldehydes by allylic cyclic carbonates with SnCl2 proceeded smoothly tto afford 1,3-diols with high diastereocontrol. For the exomethylene cyclic carbonate, allylation with aldehydes furnished 1,4-diols or 1

Palladium-catalysed carbonyl allylation by 2-methylenepropane-1,3-diol

2-Methylenepropane-1,3-diol first allylates an aldehyde exclusively at the allylic alcohol moiety at room temperature and then, at 50°C, allylates another aldehyde also at the allylic alcohol moiety, in the presence of a catalytic amount of PdCl2(PhCN)2 with tin(II) chloride.