55403-25-3

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-CHLORO-4-NITRO-PHENYL)-PIPERIDINE is used as a building block for the synthesis of various drugs and bioactive molecules. Its unique structural properties allow it to serve as a key component in the development of new pharmaceuticals, targeting a range of diseases and conditions.
Used in Chemical Synthesis:
In addition to its pharmaceutical applications, 1-(2-CHLORO-4-NITRO-PHENYL)-PIPERIDINE is also utilized as a chemical intermediate in the synthesis of other organic compounds. Its versatile structure makes it a valuable asset in the creation of a wide array of chemical products.
Used in Medical and Pharmacological Research:
Due to its potential to interact with various biological targets, 1-(2-CHLORO-4-NITRO-PHENYL)-PIPERIDINE is being researched for its possible application in medicine and pharmacology. This includes the development of new therapeutic strategies and the enhancement of existing treatments for various diseases.

Upstream product

• 110-89-4 piperidine 
• 350-30-1 3-chloro-4-fluoronitrobenzene 
• 626-67-5 N-methylcyclohexylamine 
• 99-54-7 3,4-dichloronitrobenzene 

Downstream Products

• 55403-26-4 3-Chloro-4-piperidin-1-yl-phenylamine 

Relevant academic research and scientific papers

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with a defect in glyoxylate metabolism, for example a disease or disorder associated with the enzyme glycolate oxidase (GO) or alterations in oxalate metabolism. Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

Reaction of Mono-, Di-, and Trichloronitrobenzenes with N-Methyl Substituted Cyclic Tertiary Amines under High Pressure

The reactions of mono-, di-, and trichloronitrobenzenes with 1-methylpyrrolidine under high pressure gave products of demethylation and ring-opening through a quaternary pyrrolidinium chloride intermediate formed by the SNAr reaction.On the other hand, the reactions with 1-methylpiperidine and 4-methylmorpholine gave only demethylation products.The selectivities of the resctions of 1-methylpyrrolidine with these chloronitrobenzenes were found to be effected by the neighboring substituent to the pyrrolidinium group.

9-(P-phenylazoanilino)-7-methyl-1H-imidazo[4,5-f]quinolines

A series of 9-(substituted amino)imidazo[4,5-f]quinolines are effective anthelmintic agents; particularly in respect to the tapeworm Hymenolepis nana.