55404-31-4

Usage

Uses

Used in Pharmaceutical Industry:
3-Bromo-2-chloro-4-picoline is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of complex organic molecules with potential therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Bromo-2-chloro-4-picoline serves as an intermediate in the production of agrochemicals, aiding in the creation of compounds that can enhance crop protection and yield.
Used in Organic Synthesis:
3-Bromo-2-chloro-4-picoline is utilized as a building block in organic synthesis, particularly for the production of complex organic molecules, due to its reactive bromine and chlorine substituents which allow for further chemical reactions to create diverse chemical entities.

InChI:InChI=1/C6H5BrClN/c1-4-2-3-9-6(8)5(4)7/h2-3H,1H3

Upstream product

• 17117-15-6 3-bromo-4-methyl-1-oxidopyridin-1-ium 
• 3430-22-6 3-Bromo-4-methylpyridin 
• 133627-45-9 3-Amino-2-chloro-4-methylpyridine 

Downstream Products

• 1003312-15-9 2-(4-methoxybenzyloxy)-3-bromo-4-methylpyridine 
• 851607-30-2 3-bromo-5-chloro-2-methoxy-4-methylpyridine 
• 1429510-98-4 5-(2,4-dimethoxybenzyl)-7-(2-methoxy-4-methylpyridin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[4,3-c]quinolin-4(5H)-one 
• 1429510-99-5 5-(2,4-dimethoxybenzyl)-7-(2-ethoxy-4-methylpyridin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[4,3-c]quinolin-4(5H)-one 
• 18368-59-7 3-bromo-4-methyl-1H-pyridin-2-one 

Relevant academic research and scientific papers

MACROCYCLIC DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE DISEASES

The invention relates to compounds of formula (Φ) as further defined herein and to the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to the uses thereof. The compounds and salts of the present invention inhibit anaplastic lymphoma kinase (ALK) and/or EML4-ALK and are useful for treating or ameliorating abnormal cell proliferative disorders, such as cancer.

PYRAZOLOQUINOLINE DERIVATIVES

A compound and/or pharmacologically acceptable salt thereof represented by the formula (I) has PDE9 inhibitory action, so that the intracerebral cGMP concentration is anticipated to be elevated. The PDE9 inhibitory action and the increase in cGMP lead to the improvement of learning and memory behaviors, and the compound (I) has applicability as a therapeutic agent for cognitive dysfunctions in Alzheimer's disease. wherein R1 is a hydrogen atom; R2 is an aromatic ring group, etc.; R3 is a hydrogen atom, etc; R4 is a hydrogen atom; R5 is an oxepanyl group, etc.; R6 is a hydrogen atom.