55420-73-0Relevant academic research and scientific papers
Thermal decarboxylative Nazarov cyclization of cyclic enol carbonates involving chirality transfer
Kozuma, Akane,Komatsuki, Keiichi,Saito, Kodai,Yamada, Tohru
supporting information, p. 60 - 63 (2019/12/12)
Decarboxylative Nazarov cyclization of chiral cyclic enol carbonates proceeded to afford chiral 2-cyclopentenones with excellent chirality transfer under thermal conditions without any catalyst. Interestingly, the thermal decarboxylative Nazarov cyclization furnished the desired product with better chirality transfer than the Lewis acid-catalyzed reaction.
Role of Ring Ortho Substituents on the Configuration of Carotenoid Polyene Chains
Kim, Minsoo,Jung, Hyunuk,Aragonès, Albert C.,Díez-Pérez, Ismael,Ahn, Kwang-Hyun,Chung, Wook-Jin,Kim, Dahye,Koo, Sangho
supporting information, p. 493 - 496 (2018/01/28)
The 9-(Z)-configuration was exclusively obtained in the carotenoid polyene chain irrespective of olefination and disconnection methods for terminal ortho-unsubstituted benzene rings. The 2,6-dimethyl substituents in the terminal rings secure an all-(E)-po
Microwave-assisted InCl3-catalyzed Meyer-Schuster rearrangement of propargylic aryl carbinols in aqueous media: a green approach to α,β-unsaturated carbonyl compounds
Cadierno, Victorio,Francos, Javier,Gimeno, José
experimental part, p. 4773 - 4776 (2011/03/19)
A novel, efficient, simple and environmentally benign protocol for the Meyer-Schuster isomerization of propargylic aryl carbinols into α,β-unsaturated carbonyl compounds has been developed using catalytic amounts of InCl3, pure water as the solvent, and microwave irradiation as the heating source.
Synthesis and cell growth inhibitory properties of substituted (E)-1-phenylbut-1-en-3-ones
Ducki, Sylvie,Hadfield, John A.,Hepworth, Lucy A.,Lawrence, Nicholas J.,Ching-Ying, Liu,McGown, Alan T.
, p. 3091 - 3094 (2007/10/03)
A series of (E)-1-phenylbut-1-en-3-ones, based on the naturally occurring (E)-1-(4'-hydroxyphenyl)but-1-en-3-one [IC50 (K562) 60 μM], was synthesised and screened for cytotoxic activity against the K562 human leukaemia cell line. (E)-1-(Pentafluorophenyl)but-1-en-3-one [IC50 (K562) 1.8 μM] was found to be over 30-fold more active than 1.
Mannich Bases of 4-Phenyl-3-buten-2-one: A New Class of Antiherpes Agent
Edwards, M.L.,Ritter, H.W.,Stemerick, D.M.,Stewart, K.T.
, p. 431 - 436 (2007/10/02)
The morpholine Mannich base of 4-phenyl-3-buten-2-one was found to have activity in model infections of herpes simplex.The activity was essentially equivalent to that of disodium phosphonoacetate.This paper presents the biological activity and synthesis o
