55441-41-3Relevant academic research and scientific papers
Synthesis and anticancer activity of novel 2-alkylthio-4-amino-5-(thiazol-2-YL)pyrimidines
Bunev, Alexander S.,Khochenkov, Dmitry A.,Khochenkova, Yulia A.,Machkova, Yulia S.,Varakina, Elena V.,Gasanov, Rovshan E.,Troshina, Marina A.,Avdyakova, Olga S.
supporting information, p. 2521 - 2527 (2021/06/25)
A series of new fist-time synthesized of thiazolyl-substituted 4-aminopyrimidine was obtained on the basis of a two-stage process including thioamidation of 4-amino-5-cyanopyrimide followed by one-pot acylation and Hantzsch synthesis in good yield (52–77%
4-Amino-2-substituted-5-pyrimidinecarboxamidoximes and carbothioamides
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, (2008/06/13)
4-Amino-2-substituted-5-pyrimidinecarboxamidoximes and carbothioamides are immunomodulatory agents useful in the treatment of immune system diseases and disorders.
