55441-53-7 Usage
Uses
Used in Pharmaceutical and Medicinal Chemistry:
4-AMINO-2-(1-PYRROLIDINYL)-5-PYRIMIDINECARBONITRILE is used as a building block for the synthesis of various bioactive molecules, contributing to the development of new drugs and therapeutic agents. Its unique structure allows for the creation of compounds with potential medicinal properties.
Used in Organic Synthesis and Chemical Research:
In the field of organic synthesis, 4-AMINO-2-(1-PYRROLIDINYL)-5-PYRIMIDINECARBONITRILE serves as a valuable reagent, facilitating the creation of complex organic compounds and aiding in the advancement of chemical research. Its presence in reactions can lead to the discovery of novel chemical entities with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 55441-53-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,4,4 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 55441-53:
(7*5)+(6*5)+(5*4)+(4*4)+(3*1)+(2*5)+(1*3)=117
117 % 10 = 7
So 55441-53-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H11N5/c10-5-7-6-12-9(13-8(7)11)14-3-1-2-4-14/h6H,1-4H2,(H2,11,12,13)
55441-53-7Relevant academic research and scientific papers
A Novel Solution- and Solid-Phase Approach to 2,4,5-Tri- and 2,4,5,6-Tetrasubstituted Pyrimidines and Their Conversion into Condensed Heterocycles
Masquelin, Thierry,Sprenger, Daniel,Baer, Roman,Gerber, Fernand,Mercadal, Yves
, p. 646 - 660 (2007/10/03)
A novel general synthesis of 2,4,5-tri- and 2,4,5,6-tetrasubstituted pyrimidines 5a-d and 7a, e, f, g by condensation of thiouronium salts of type 3 with (ethoxymethylidene)malononitrile (4) and [bis(methylthio)methylidene]malononitrile (6), respectively, was first established in solution (Scheme 1) and successfully transferred onto solid support by using the polymer-bound thiouronium salt 11 (Scheme 3). Further investigations were directed toward a multidirectional cleavage procedure of the 2-(alkylsulfinyl) intermediates, obtained from the 2-(alkylthio)pyrimidines 7a (Scheme 2) or 12 and 14 (Schemes 3 and 4), with different nucleophiles to form highly substituted pyrimidines. In addition, fused-heterocycle derivatives 22a-h, 24a-c, and 26a-e were generated in good-to-excellent yields by condensation of 7a, e, h with versatile isocyanates and isothiocyanates, with subsequent alkylation (Scheme 5).
Xn:Harmful;
