554430-15-8

Basic information

• Product Name: 2H-1-Benzopyran-4-methanol, 7-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-[4-[[(1,1-dimethylethyl)dimethyl silyl]oxy]-2-hydroxyphenyl]-a-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-
• CAS NO: 554430-15-8
• Molecular Formula: C40H57NO6Si2
• Molecular Weight: 704.067
• Mol File: 554430-15-8.mol

Chemical Properties

• CAS DataBase Reference: 2H-1-Benzopyran-4-methanol, 7-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-[4-[[(1,1-dimethylethyl)dimethyl silyl]oxy]-2-hydroxyphenyl]-a-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran-4-methanol, 7-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-[4-[[(1,1-dimethylethyl)dimethyl silyl]oxy]-2-hydroxyphenyl]-a-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-(554430-15-8)
• EPA Substance Registry System: 2H-1-Benzopyran-4-methanol, 7-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-[4-[[(1,1-dimethylethyl)dimethyl silyl]oxy]-2-hydroxyphenyl]-a-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-(554430-15-8)

Safety Data

• Hazardous Substances Data: 554430-15-8(Hazardous Substances Data)

Upstream product

• 554430-67-0 1-[2-(4-iodophenoxy)ethyl]pyrrolidine 
• 553681-47-3 2,8-bis(tert-butyl-dimethyl-silyloxy)-5,11-dihydro-chromeno[4,3-c]chromen-5-ol 
• 554430-69-2 2,8-dihydroxy-11H-chromeno[4,3-c]chromen-5-one 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 554430-87-4 2,8-bis(tert-butyl-dimethyl-silyloxy)-11H-chromeno[4,3-c]chromen-5-one 

Downstream Products

• 554430-92-1 1-(2{-4-[2,8-bis-(tert-butyl-dimethyl-silyloxy)-5,11-dihydro-chromeno[4,3-c]-chromen-5-yl]-phenoxy}-ethyl)-pyrrolidine 

Relevant articles and documents

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Novel heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators

The present invention is directed to novel heteroatom containing tetracyclic derivatives, pharmaceutical compositions containing them, their use in the treatment and/or prevention of disorders mediated by one or more estrogen receptors and processes for their preparation. The compounds of the invention are useful in the treatment and/or prevention of disorders associated with the depletion of estrogen such as hot flashes, vaginal dryness, osteopenia and osteoporosis; hormone sensitive cancers and hyperplasia of the breast, endometrium, cervix and prostate; endometriosis, uterine fibroids, osteoarthritis and as contraceptive agents, alone or in combination with a progestogen or progestogen antagonist.