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5545-54-0

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5545-54-0 Usage

General Description

Z-TYR(TBU)-OH, also known as tert-butyl (2S)-2-(((tert-butoxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoate, is a chemical compound used in the production of pharmaceuticals and research applications. It is a derivative of the amino acid tyrosine, with a tert-butyl group attached to the amino and carboxylic acid functional groups to protect them from unwanted reactions during synthesis. Z-TYR(TBU)-OH is often used as a building block in peptide synthesis, allowing for the incorporation of tyrosine residues in the creation of specific peptide sequences. Its stability and compatibility with various chemical reactions make it a valuable tool for the design and production of novel pharmaceutical compounds and research peptides.

Check Digit Verification of cas no

The CAS Registry Mumber 5545-54-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,4 and 5 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5545-54:
(6*5)+(5*5)+(4*4)+(3*5)+(2*5)+(1*4)=100
100 % 10 = 0
So 5545-54-0 is a valid CAS Registry Number.

5545-54-0 Well-known Company Product Price

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  • (Code)Product description
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  • Alfa Aesar

  • (H66762)  N-Benzyloxycarbonyl-O-tert-butyl-L-tyrosine, 98%   

  • 5545-54-0

  • 5g

  • 365.0CNY

  • Detail
  • Alfa Aesar

  • (H66762)  N-Benzyloxycarbonyl-O-tert-butyl-L-tyrosine, 98%   

  • 5545-54-0

  • 25g

  • 1392.0CNY

  • Detail
  • Alfa Aesar

  • (H66762)  N-Benzyloxycarbonyl-O-tert-butyl-L-tyrosine, 98%   

  • 5545-54-0

  • 100g

  • 4508.0CNY

  • Detail

5545-54-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (S)-2-(((Benzyloxy)carbonyl)amino)-3-(4-(tert-butoxy)phenyl)propanoic acid

1.2 Other means of identification

Product number -
Other names (2S)-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]-2-(phenylmethoxycarbonylamino)propanoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5545-54-0 SDS

5545-54-0Downstream Products

5545-54-0Relevant articles and documents

A N-(9-fluorenylmethyloxycarbonyl)-O-tert-butyl-L-tyrosine method for the preparation of

-

Paragraph 0045; 0048, (2017/04/11)

The invention relates to a method for preparing N-(9-fluorenylmethoxy carbony)-O-tertiary butyl-L-tyrosine. The problem that an enantiomer is easily generated is solved. The method comprises the following synthetic steps: (1) dissolving L-Tyr into a methanol solution, adding SOCl2 and then carrying out reflux reaction, so as to obtain Tyr-OMe.HCl; (2) dissolving the Tyr-OMe.HCl into a water solution, adding AcOEt and Na2CO3 and then reacting with Z-Cl, and controlling the pH of the system at 7-10, so as to obtain Z-L-Tyr-OMe; (3) dissolving the Z-L-Tyr-OMe into a CH2Cl2 solution, adding H2SO4 and isobutene, reacting at normal temperature for 1-10 days, so as to obtain Z-L-Tyr(tBu)-OMe; (4) adding the NaOH solution to the Z-L-Tyr(tBu)-OMe to react, so as to obtain Z-L-Tyr(tBu); (5) dissolving the Z-L-Tyr(tBu) into methanol, adding Pd/C, and leading in hydrogen to react, so as to obtain L-Tyr(tBu); (6) dissolving Z-L-Tyr(tBu) into the water solution, adding the Na2CO3 and THF and then reacting with Fmoc-osu, and controlling the pH of the system at 8-10, so as to obtain Fmoc-Tyr(tBu). By adopting the method, generation of the enantiomer is avoided, and the citric acid is taken as an acidifier, so that the product is more stable, and the reaction processes do not relate to high-temperature and high-pressure reaction, and the method is applicable to large-scale production.

N,N-dialkylated leucine enkephalins as potential δ opioid receptor antagonists

Lovett,Portoghese

, p. 1144 - 1149 (2007/10/02)

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