55453-06-0

Basic information

• Product Name: Pyrazine, 2,5-bis(4-bromophenyl)-
• Synonyms: 2,5-Di-p-bromphenylpyrazin;2,5-di-p-bromophenylpyrazine
• CAS NO: 55453-06-0
• Molecular Formula: C16H10Br2N2
• Molecular Weight: 390.077
• Mol File: 55453-06-0.mol

Chemical Properties

• CAS DataBase Reference: Pyrazine, 2,5-bis(4-bromophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrazine, 2,5-bis(4-bromophenyl)-(55453-06-0)
• EPA Substance Registry System: Pyrazine, 2,5-bis(4-bromophenyl)-(55453-06-0)

Safety Data

• Hazardous Substances Data: 55453-06-0(Hazardous Substances Data)

Upstream product

• 99-73-0 para-bromophenacyl bromide 
• 88419-02-7 3-(2-(4-bromophenyl)-2-oxoethyl)thiazolidine-2,4-dione 
• 74-89-5 methylamine 
• 1233843-50-9 (Z)-2-bromo-1-(4-bromophenyl)vinyl acetate 
• 109-09-1 2-chloropyridine 
• 17631-26-4 3-(4-bromophenyl)-2H-azirine 
• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 23229-26-7 2-5-dibromopyrazine 
• 5467-74-3 4-Bromophenylboronic acid 
• 89108-50-9 1-(1-azidovinyl)-4-bromobenzene 

Relevant articles and documents

Effect of conjugation on the optoelectronic properties of pyrazine-based push-pull chromophores: Aggregation-induced emission, solvatochromism, and acidochromism

A series of pyrazine-based bipodal D-π-A-π-D and D-π-A-π-A molecules with multi-stimuli response have been synthesized via Suzuki and Sonogashira cross-coupling reactions. We present a joint theoretical and experimental study to elucidate structure-property relationship of these push-pull chromophores. The modification of the end-capped donor-acceptor units and the extension of π-conjugation are key factors in tuning their optical, thermal and electrochemical properties. Depending on the different electron-donating substituents, the chromophores emit blue to orange fluorescence. The solvent dependent emission was observed and their Dimroth-Reichardt plots show a linear correlation. The aggregation-induced study shows enhanced emission in aggregates. Our work has elucidated that these small structural isomers can be utilized to develop a promising multi-stimuli responsive fluorescent materials.

Synthesis of Imidazo[1,2- a]pyridines: Triflic Anhydride-Mediated Annulation of 2 H-Azirines with 2-Chloropyridines

The discovery and optimization of a reaction between 2-chloropyridines and 2H-azirines producing imidazo[1,2-a]pyridines is described. The treatment of 2H-azirines with triflic anhydride (Tf2O) forms an electrophilic 1-trifloyl-aziridin-2-yl triflate spec

Highly efficient synthesis of 2,5-disubstituted pyrazines from (Z)-β-haloenol acetates

A highly efficient synthesis of a wide range of 2,5-disubstituted pyrazines from (Z)-β-haloenol acetates is described. The reactions are conducted under convenient conditions and provide products with excellent regioselectivity in moderate to excellent yields with a broad substrate scope, including a variety of aromatic and aliphatic haloenol acetates.

RECYCLIZATION REACTIONS. RECYCLIZATIONS OF 3-ACYLMETHYL-2,4-THIAZOLIDINEDIONES BY THE ACTION OF NUCLEOPHILES

Four directions were established and investigated in the recyclization of 3-acylmethyl-2,4-thiazolidinediones with the participation of the side chain at the cyclic nitrogen atom and the formation of substituted 2-imidazolones or 2-oxazolones (under the influence of ammonia or hydroxides respectively), 2,5-diarylpyrazines (under the influence of methylamine), 6-monosubstituted or 2,6-disubstituted 4,5-dihydro-1,2,4-triazin-3-ones, and 5-substituted 1-amino-2-imidazolones (under the influence of hydrazine and phenylhydrazine).The directions of recyclization with hydrazines are determined by the stereochemical configuration of the intermediate hydrazones; the E-hydrazones of 3-acylmethyl-2,4-thiazolidenediones are converted into 4,5-dihydro-1,2,4-triazin-3-ones, while the Z izomers are converted into 1-amino-2-imidazolones.