55456-42-3Relevant academic research and scientific papers
Regio- and stereoselective α-alkylation of N-terminal amino acid residue of peptides using a pyridoxal model compound with a chiral ansa-structure
Miyashita, Kazuyuki,Iwaki, Hiroshi,Tai, Kuninori,Murafuji, Hidenobu,Sasaki, Naoko,Imanishi, Takeshi
, p. 5773 - 5780 (2007/10/03)
Regio- and stereoselective α-alkylation of N-terminal amino acid residue of peptides was achieved by Li+-mediated alkylation of aldimines prepared from the peptides and a pyridoxal model compound having a chiral ansa-structure and an ethoxyetho
α-Alkylation of α-amino esters by using a pyridoxal model compound having a Li+-ionophore character
Miyashita, Kazuyuki,Miyabe, Hideto,Kurozumi, Chiaki,Tai, Kuninori,Imanishi, Takeshi
, p. 12125 - 12136 (2007/10/03)
Synthesis of α,α-dialkyl-α-amino esters by α-alkylation of aldimines prepared from a novel pyridoxal model compound was studied. The α-alkylation of the aldimines having an ethoxy-ethoxy group at C-3 proceeded most rapidly when LiOH was employed as a base and gave α,α-dialkyl-α-amino esters after hydrolysis. The chelated structure composed of the aldimine and Li+ was also revealed by 1H-NMR analysis.
Efficient α-Alkylation of α-Amino Acids by Means of a Novel Pyridoxal Model Compound
Miyashita, Kazuyuki,Miyabe, Hideto,Kurozumi, Chiaki,Imanishi, Takeshi
, p. 487 - 488 (2007/10/03)
α-Alkyl-α-amino esters were prepared by the alkylation of α-imino esters obtained from α-amino acids and a novel PLP model compound possessing a Li+ ionophore character.
