55467-95-3

Basic information

• Product Name: Benzenamine, N-(3-chloropropyl)-
• CAS NO: 55467-95-3
• Molecular Formula: C9H12ClN
• Molecular Weight: 169.654
• Mol File: 55467-95-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenamine, N-(3-chloropropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, N-(3-chloropropyl)-(55467-95-3)
• EPA Substance Registry System: Benzenamine, N-(3-chloropropyl)-(55467-95-3)

Safety Data

• Hazardous Substances Data: 55467-95-3(Hazardous Substances Data)

Upstream product

• 6940-76-7 1-iodo-3-chloro-propane 
• 62-53-3 aniline 
• 109-70-6 1.3-chlorobromopropane 

Downstream Products

• 87962-87-6 4-(phenylamino)butanoic acid 
• 1285616-99-0 N-(3-(4-(4-cyanophenyl)-piperazin-1-yl)-propyl)-4-fluoro-N-phenylbenzamide 
• 1285616-97-8 4-fluoro-N-phenyl-N-(3-(4-p-tolylpiperazin-1-yl)-propyl)-benzamide 
• 1285616-96-7 4-fluoro-N-(3-(4-(4-fluorophenyl)-piperazin-1-yl)-propyl)-N-phenylbenzamide 
• 1285616-95-6 4-fluoro-N-phenyl-N-(3-(4-p-tolylpiperazin-1-yl)-propyl)-benzenesulfonamide 
• 1285616-93-4 N-phenyl-N-(3-(4-p-tolylpiperazin-1-yl)-propyl)-benzenesulfonamide 
• 1285616-91-2 N-(3-(4-methylpiperazin-1-yl)-propyl)-N-phenylbenzamide 
• 1285616-87-6 4-chloro-N-phenyl-N-(3-(4-p-tolylpiperazin-1-yl)-propyl)-benzamide 
• 1285616-86-5 N-phenyl-N-(3-(4-p-tolylpiperazin-1-yl)-propyl)benzamide 
• 1285616-84-3 N-phenyl-N-(3-(4-phenylpiperazin-1-yl)-propyl)-benzamide 
• 1285616-78-5 N-(3-chloropropyl)-N-phenylbenzenesulfonamide 
• 1285616-73-0 4-chloro-N-(3-chloropropyl)-N-phenylbenzamide 
• 1285616-70-7 N-(3-chloropropyl)-N-phenylbenzamide 
• 1285616-75-2 N-(3-chloropropyl)-4-fluoro-N-phenylbenzamide 

Relevant articles and documents

Substituted piperazines as novel potential radioprotective agents

The increasing risk of radiation exposure underlines the need for novel radioprotective agents. Hence, a series of novel 1-(2-hydroxyethyl)piperazine derivatives were designed and synthesized. Some of the compounds protected human cells against radiation-

Synthesis and biological evaluation of novel N-[3-(4-phenylpip-erazin-1-yl) -propyl]-carboxamide derivatives

A series of novel N-[3-(4-phenylpiperazin-1-yl)-propyl]-carboxamide derivatives were synthesised and studied for the potential treatment of HIV. These compounds were obtained through the efficient synthetic route that involved microwave assisted synthesis. These new compounds have been characterised by IR,1H NMR, MS and elemental analysis. The cell-cell fusion inhibitory activities of the compounds have also been evaluated.

4,4'-Di-tert-butylbiphenyl-Catalysed Reductive Opening of Azetidines with Lithium: A Direct Preparation of 3,N-Dilithioalkylamines

The reaction of N-phenylazetidine 1a with an excess of lithium powder and a catalytic amount of 4,4'-di-tert-butylbiphenyl (5 molpercent) in THF at -15 deg C leads to the corresponding dianion 2a, which by treatment with different electrophiles (H2O, D2O, ButCHO, PhCHO, (CH2)5CO, PhCH=NPh, CO2) yields, after hydrolysis with water, the expected functionalysed amines 3aa-ah.The same method applied to N-isopropyl-2-phenylazetidine 1c affords compounds 3ca-ce (electrophiles: H2O, D2O, PhCHO, Me2CO, CH2=CHCH2Br) resulting from the more stable benzylic intermediate 2c.Finally, the regiochemistry in the reductive opening of 2-methyl-N-phenylazetidine 1d followed by deuterolysis was studied: a mixture of both regioisomers 3da+3da' was obtained, the ratio being the oposite as expected according to the stability of both intermediates 2d and 2d'.