55480-59-6Relevant academic research and scientific papers
A convenient general synthesis of 3-substituted 2H-chromene derivatives
Kaye, Perry T.,Nocanda, Xolani W.
, p. 1318 - 1323 (2002)
Reactions of 2-hydroxybenzaldehydes and 2-hydroxy-1-naphthaldehydes with various activated alkenes under Baylis-Hillman conditions have been shown to proceed with regioselective cyclisation to afford the corresponding 3-substituted chromene derivatives. In some cases competitive dimerisation of the alkene component was observed, and direct dimerisation in the absence of the aldehyde has been explored.
