55486-13-0

Usage

Uses

1-Pyrenebutyric hydrazide is a fluorescent labeling reagent.

InChI:InChI=1/C20H18N2O/c21-22-18(23)6-2-3-13-7-8-16-10-9-14-4-1-5-15-11-12-17(13)20(16)19(14)15/h1,4-5,7-12H,2-3,6,21H2,(H,22,23)

Upstream product

• 70570-29-5 4-(1-pyrene)butyric acid methyl ester 
• 63549-37-1 4-(pyren-1-yl)butyryl chloride 
• 114932-60-4 4-(1-pyrene)butyric acid N-hydroxysuccinimide ester 
• 3443-45-6 1-pyrenebutyric acid 

Downstream Products

• 1436419-69-0 C₃₉H₃₁N₂OP 
• 1240105-42-3 C₄₇H₆₂N₂O₃ 

Relevant academic research and scientific papers

N-Amidothiourea based PET chemosensors for anions

Neutral N-amidothiourea based PET anion sensors bearing a pyrene fluorophore, 1-3, were synthesized and their fluorescent response toward anions was assessed. The anion quenching and binding constants were found to be much higher than those of the corresponding PET sensors bearing a simple thiourea receptor despite a higher oxidation potential of the electron donor and a relatively longer spacer (CH2)3 between the signal reporter and binding receptor in 1-3. This was explained in terms of a much more substantial increase in the electron donating ability of amidothiourea upon anion binding. The Royal Society of Chemistry.

A thermo-responsive supramolecular hydrogel that senses cholera toxin: Via color-changing response

A Pyrene-based amphiphile with C4-alkanoyl spacer and lactose (PyLac) self-assembles in the aqueous media to form an injectable hydrogel. It shows preferential binding with Cholera Toxin (CT) via its terminal galactose residue, and hence can be employed for the selective detection of CT via color-changing response.

Cu2+-selective turn-on fluorescence signaling based on metal-induced hydrolysis of pyrenecarbohydrazide

We developed a simple Cu2+-selective turn-on fluorescence signaling probe based on the hydrolysis of 1-pyrenecarbohydrazide (1) to 1-pyrenecarboxylic acid. Probe 1 exhibited prominent fluorescence signaling of Cu2+ ions in a 10% aqueous Tris-buffered (pH 7.0) DMSO solution with a detection limit of 5.93?×?10?8?M. Signaling with control compounds derived from pyreneacetic acid and pyrenebutyric acid showed that the fluorescence signal became less pronounced as the distance between the hydrazide functionality and the pyrene fluorophore increased. As a practical application, this probe was employed for the determination of Cu2+ in a simulated semiconductor wastewater.