55488-51-2

Usage

Uses

Used in Pharmaceutical Industry:
Carbonochloridic acid, decyl ester is used as a reagent for the preparation of (S)-(+)-N-decoxycarbonyl-leucine, a chiral surfactant. This chiral surfactant is essential in the pharmaceutical industry for the synthesis of various drugs, particularly those requiring enantiomeric purity.
Used in Chemical Synthesis:
In the chemical synthesis industry, carbonochloridic acid, decyl ester is used to synthesize decyl chloride via decarboxylation in the presence of dimethylformamide. Decyl chloride is an important intermediate in the production of various chemicals and materials, such as surfactants, lubricants, and plasticizers.
Used in Research and Development:
Carbonochloridic acid, decyl ester is also utilized in research and development for the exploration of new chemical reactions and the synthesis of novel compounds. Its unique reactivity and properties make it a valuable tool for chemists in various fields, including organic chemistry, materials science, and pharmaceutical chemistry.

InChI:InChI=1/C11H21ClO2/c1-2-3-4-5-6-7-8-9-10-14-11(12)13/h2-10H2,1H3

Upstream product

• 112-30-1 1-Decanol 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 75-44-5 phosgene 

Downstream Products

• 133230-93-0 2-Decyloxycarbonylamino-3-phenyl-propionic acid 
• 1002-69-3 decyl chloride 
• 34443-09-9 di-decyl peroxydicarbonate 
• 133231-05-7 S₁₀-L-Phe-L-His-OH 
• 133230-99-6 S₁₀-L-Phe-L-His-OMe 
• 66605-97-8 decyl phosphinate 

Relevant academic research and scientific papers

Anti-HIV-Active Nucleoside Triphosphate Prodrugs

We disclose a study on nucleoside triphosphate (NTP) analogues in which the γ-phosphate is covalently modified by two different biodegradable masking units and d4T as nucleoside analogue that enable the delivery of d4TTP with high selectivity in phosphate buffer (pH 7.3) and by enzyme-triggered reactions in human CD4+ T-lymphocyte CEM cell extracts. This allows the bypass of all steps normally needed in the intracellular phosphorylation. These TriPPPro-nucleotides comprising an acyloxybenzyl (AB; ester) or an alkoxycarbonyloxybenzyl (ACB; carbonate) in combination with an ACB moiety are described as NTP delivery systems. The introduction of these two different groups led to the selective formation of γ-(ACB)-d4TTPs by chemical hydrolysis and in particular by cell extract enzymes. γ-(AB)-d4TTPs are faster cleaved than γ-(ACB)-d4TTPs. In antiviral assays, the compounds are highly active against HIV-1 and HIV-2 in wild-type CEM/O cells and more importantly in thymidine kinase-deficient CD4+ T-cells (CEM/TK-).

Unsaturated cyclic ureas as new nontoxic biodegradable transdermal penetration enhancers I: Synthesis

A new concept was implemented to reduce the toxicity of some new biodegradable transdermal penetration enhancers. These enhancers consist of 1-alkyl-4-imidazolin-2-one and a long-chain alkyl ester group at the N-3 position. The synthesis involves N-alkylation of the parent compound with soft alkylating agents which were prepared in high yields by an improved method. A phase transfer catalysis technique using KOH as the base, tetrabutylammonium bromide as the catalyst, and toluene as the solvent was found to be most effective in the N-alkylation step.