55502-96-0

Usage

Uses

Used in Pharmaceutical Synthesis:
2-Amino-4,5-dimethylthiophene-3-carboxylic acid serves as a key building block in the synthesis of various pharmaceuticals. Its versatile reactivity and potential biological activities contribute to the development of new drugs with improved efficacy and safety profiles.
Used in Agrochemical Development:
In the agrochemical industry, 2-Amino-4,5-dimethylthiophene-3-carboxylic acid is utilized as a starting material for the creation of novel agrochemicals. Its unique properties allow for the design of innovative compounds with enhanced pesticidal or herbicidal properties, contributing to more effective and sustainable agricultural practices.
Used as a Ligand in Coordination Chemistry:
2-Amino-4,5-dimethylthiophene-3-carboxylic acid also finds application as a ligand in coordination chemistry. Its ability to form stable complexes with metal ions makes it a useful component in the synthesis of coordination compounds with potential applications in catalysis, materials science, and other areas of research.
Organic Synthesis:
2-Amino-4,5-dimethylthiophene-3-carboxylic acid's unique structure and reactivity make it a valuable tool in organic synthesis, enabling the creation of a wide range of organic compounds with diverse applications across various industries.

InChI:InChI=1/C7H9NO2S/c1-3-4(2)11-6(8)5(3)7(9)10/h8H2,1-2H3,(H,9,10)

Upstream product

• 4815-24-1 2-amino-4,5-dimethyl-3-thiophenecarboxylic acid ethyl ester 

Downstream Products

• 133166-77-5 [1-(3,4-Dichloro-benzyl)-5,6-dimethyl-2,4-dioxo-1,4-dihydro-2H-thieno[2,3-d]pyrimidin-3-yl]-acetic acid 
• 268733-46-6 N-(5,6-dimethyl-4-oxo-4H-thieno[2,3-d][1,3]thiazin-2-yl)-benzamide 
• 4651-93-8 2-amino-4,5-dimethylthiophene-3-carboxylic acid methyl ester 
• 18593-44-7 5,6-dimethylthieno<2,3-d>pyrimidin-4(3H)-one 
• 1393804-94-8 7-(2,4,6-trimethylphenyl)-2,3-dimethyl-4H-thieno[2',3':4,5]-pyrimido[2,3-a]pyridazin-4-one 
• 1162684-74-3 5,6-dimethylthieno[2,3-d]pyrimidine-2,4-dicarboxylate diethyl ester 
• 18593-46-9 5,6-dimethyl-2-phenylthieno<2,3-d>pyrimidin-4(3H)-one 
• 63274-60-2 5,6-dimethyl-2-phenyl-4H-thieno[2,3-d][1,3]oxazin-4-one 

Relevant academic research and scientific papers

Straightforward synthesis, characterization, and cytotoxicity evaluation of hybrids of natural alkaloid evodiamine/rutaecarpine and thieno[2,3-d]pyrimidinones

Dozens of hybrids of natural alkaloid evodiamine/rutaecarpine and thieno[2,3-d]pyrimidinones were synthesized in a straightforward method by condensation of substituted 2H-thieno[2,3-d][1, 3]oxazine-2,4(1H)-diones or N-methyl-2H-thieno[2,3-d][1, 3]oxazine-2,4(1H)-dione with 3,4-dihydro-β-carbolines. In vitro cytotoxic assay discovered that compounds 9a, 10e, 11a, 11d, 11f, and 12a could induce antiproliferation against four different types of human cancer cells while compounds 10f and 12e were inactive. Notably, compound 11a displayed potent cell cytotoxicity for human non-small cell lung cancer cells A549, PC-9, human prostate cancer cells PC-3, and human breast cancer cell line MCF-7. Furthermore, compound 11a exhibited strong colony formation inhibition to A549 cells. These results unfold potential anticancer therapeutic applications of hybrids of thieno[2,3-d]pyrimidinones and quinazolinones.

Thienopyridine-carboxylic acid derivatives

Novel thienopyridine-carboxylic acid derivatives, which are shown by the general formula SPC1 Wherein R1 represents hydrogen or a lower alkyl; R2 represents hydrogen, a lower alkyl or a halogen; or R1 and R2, taken together, may represent an alkylene to form a 5- or 6-membered ring with or without alkyl substituents; each of R4 and R5 represents hydrogen or a lower alkyl; and their pharmaceutically acceptable salts obtainable when R4 is hydrogen, which are useful medicines such as chemotherapeutic agents of bacterial infections.