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Bis(Trimethylsilyl) hydrogen phosphate, with the chemical formula ((CH3)3SiO)2POH, is a colorless liquid chemical compound. It is known for its role as a reagent in organic synthesis and as a protective group for hydroxyl groups in organic chemistry. This versatile compound is also recognized for its utility as a cross-linking agent and a precursor in the synthesis of organophosphorus compounds, playing a significant part in the production of adhesives, coatings, sealants, pharmaceuticals, and agrochemicals. However, due to its potential toxicity, reactivity with water, and environmental hazards, careful handling is imperative.

55518-04-2

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55518-04-2 Usage

Uses

Used in Organic Synthesis:
Bis(Trimethylsilyl) hydrogen phosphate is used as a reagent for facilitating various organic synthesis processes, capitalizing on its ability to protect hydroxyl groups and participate in cross-linking reactions.
Used in Adhesives, Coatings, and Sealants Production:
In the manufacturing industry, bis(Trimethylsilyl) hydrogen phosphate is utilized as a cross-linking agent, enhancing the durability and performance of adhesives, coatings, and sealants.
Used in Pharmaceutical Production:
bis(Trimethylsilyl) hydrogen phosphate serves as a precursor in the synthesis of organophosphorus compounds, which are integral in the development of pharmaceuticals, contributing to the creation of new drugs and therapies.
Used in Agrochemical Production:
Similarly, in the agrochemical sector, bis(Trimethylsilyl) hydrogen phosphate is employed as a precursor for the synthesis of organophosphorus compounds that are vital in the formulation of pesticides and other agricultural chemicals.
Used in Preparation of Phosphate Esters:
Bis(Trimethylsilyl) hydrogen phosphate is also used in the preparation of various phosphate esters, which have diverse applications across different industries, including as additives in lubricants and fuel.

Check Digit Verification of cas no

The CAS Registry Mumber 55518-04-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,5,1 and 8 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 55518-04:
(7*5)+(6*5)+(5*5)+(4*1)+(3*8)+(2*0)+(1*4)=122
122 % 10 = 2
So 55518-04-2 is a valid CAS Registry Number.

55518-04-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name bis(trimethylsilyl) hydrogen phosphate

1.2 Other means of identification

Product number -
Other names bis-trimethylsilylhydrogenphosphate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:55518-04-2 SDS

55518-04-2Upstream product

55518-04-2Downstream Products

55518-04-2Relevant academic research and scientific papers

PHOSPHORYLATION OF HYDROXY GROUPS VIA SILYLATED INTERMEDIATES

Montero, Jean-Louis,Toiron, Catherine,Clavel, Jean-Louis,Imbach, Jean-Louis

, p. 570 - 572 (1988)

Biologically interesting allylic phosphates have been prepared by a novel route starting from silylated alcohols.

Nonaqueous synthesis of molecular zinc amide phosphate

Chyba, Jan,Moravec, Zdenek,Necas, Marek,Mathur, Sanjay,Pinkas, Jiri

, p. 197 - 203 (2013/11/06)

Three new molecular zinc compounds were prepared by nonaqueous reactions of Zn[N(SiMe3)2]2 and ZnEt2 with trimethylsilylesters of phosphoric acid, OP(OSiMe3)3 and OP(OSiMe3)2(OH). Single-crystal X-ray diffraction analyses of crystalline products revealed molecular structures of two mononuclear complexes [ZnX2OP(OSiMe3)3] (X = N(SiMe 3)2 (1), hfacac = hexafluoroacetylacetonate, (2)) and one dinuclear zinc phosphate [(Zn{(py)N(SiMe3)2} {μ2-O2P(OSiMe3)2})2] (3). Compound 1 is only the second structurally characterized adduct of zinc bisamide with an oxygen donor and a three-coordinate Zn atom. The cyclic inorganic core {Zn(μ2-O2PO2)}2 in 3 is a model for the most common single four-ring (S4R) building unit of open-framework zinc phosphates. The molecule of 3 possesses reactive amide and trimethylsiloxy groups that can be employed in further studies on the formation of extended structures by condensation reactions. Spectroscopic properties and thermal behavior of the molecular products were examined. Compounds 1 and 3 were converted to α-Zn2P2O7 by calcination.

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