55525-92-3Relevant academic research and scientific papers
Preparation method of 4-ethyl-5-methyl-2-((2-nitrophenyl) amino) isophthalonitrile
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Paragraph 0051-0053; 0057-0059; 0063-0065; 0069-0071; 0075, (2020/12/09)
The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of 4-ethyl-5-methyl-2-((2-nitrophenyl) amino) isophthalonitrile. The 4-ethyl-5-methyl-2-((2-nitrophenyl) amino) isophthalonitrile is a main impurity
One-step method for the synthesis of aryl olefins from aryl aldehydes and aliphatic aldehydes
Borate, Hanumant B.,Gaikwad, Supriya H.,Kudale, Ananada S.,Chavan, Subhash P.,Pharande, Shrikant G.,Wagh, Vitthal D.,Sawant, Vikram S.
, p. 1528 - 1530 (2013/03/28)
A conceptually new one-step reaction affording unexpected aryl olefinic product from aromatic aldehyde, aliphatic aldehyde and malononitrile in the presence of acetic acid-ammonium acetate under mild reaction conditions without using any metal catalyst is reported. This novel reaction was used to prepare a number of substituted aryl olefins including new molecules.
One-step synthesis of 4-alkyl-3-aryl-2,6-dicyanoanilines and their use in the synthesis of highly functionalized 2,3,5,6,7- and 2,3,4,5,7-substituted indoles
Sawargave, Sangmeshwer P.,Kudale, Ananada S.,Deore, Jaydeep V.,Bhosale, Dattatry S.,Divse, Jaisingh M.,Chavan, Subhash P.,Borate, Hanumant B.
supporting information; experimental part, p. 5491 - 5493 (2011/11/04)
A three-component, one-step method for the synthesis of 4-alkyl-3-aryl-2,6-dicyanoanilines involving reaction of alkyl aldehyde, malononitrile and aryl aldehyde in presence of morpholine is reported. Highly functionalized 2,3,5,6,7- and 2,3,4,5,7-substitu
Aliphatic aldehydes in multicomponent syntheses of 4-alkyl-substituted partially hydrogenated quinolines, fused 4H-pyrans, and 2-amino-4-ethyl-5- methylbenzene-1,3-dicarbonitrile
Dyachenko,Chernega
, p. 567 - 576 (2007/10/03)
The Knoevenagel condensation of aliphatic aldehydes with CH acids, malonodinitrile, cyanothioacetamide, cyclohexane-1,3-dione, dimedone, 4-hydroxycoumarin, 3-aminophenol, and N-(cyclohex-1-enyl)-morpholine leads to formation of 4-alkyl-substituted partially hydrogenated quinolines, fused 4H-pyrans, and 2-amino-4-ethyl-5-methylbenzene-1,3-dicarbonitrile. The structure of the latter was proved by the X-ray diffraction data. Pleiades Publishing, Inc., 2006.
