5554-98-3

Upstream product

• 113541-58-5 ethyl 3-(2'-methyl-3'-furyl)propionate 
• 6947-94-0 2-methyl-3-furancarboxylic acid 
• 5555-00-0 2-methylfuran-3-carbonyl chloride 
• 113541-57-4 ethyl 3-acetoxy-3-(2'-methyl-3'-furyl)propionate 
• 113541-44-9 ethyl (2'-methyl-3'-furoyl)acetate 
• 113541-56-3 ethyl 3-hydroxy-3-(2'-methyl-3'-furyl)propionate 
• 113541-45-0 ethyl 3-(2'-methyl-3'-furyl)acrylate 

Relevant academic research and scientific papers

131. Synthesis of 2-Cycloalkenones (Parts of 1,4-Diacyl-1,3-butadiene Systems) and of a Heterocyclic Analogue by Metal-Catalyzed Decomposition of 2-Diazoacylfurans

Furans with side-chains at C(2) of various lengths terminating in diazomethyl keto groups are shown to undergo Rh2(OAc)4-catalyzed furan unravelling with the production of 2-cyclopentenone, 2-cyclohexenone, and 2-cycloheptenone to each of whose olefinic C(β) is attached an acrylaldehyde unit.Interposition of a cyclohexane or a methylaminomethylene moiety between the furan and diazoketo functions leads to the formation of a hydroindenone and pyrrolone, respectively.Replacement of the diazomethylketo terminus by an α-diazoethylketo system or a α-diazo-β-keto-ester function produces 2-substituted 2-cycloalkenones.A furan with a C4, diazomethylketo-terminating side-chain at C(3) is described to be transformed into a 4-formylmethylidene-2-cyclohexenone.