55542-27-3

Usage

Type of compound

Synthetic anabolic steroid

Parent compound

Nandrolone

Properties

Strong androgenic and anabolic properties

Veterinary use

Promotes muscle growth and improves feed efficiency in livestock

Human use

Not approved due to potential for abuse and adverse effects

Mechanism of action

Binds to androgen receptors, leading to increased protein synthesis and muscle growth

Side effects

Acne, hair loss, increased risk of liver damage

Sports use

Prohibited due to potential performance-enhancing effects

Legal status

Classified as a controlled substance in many countries

Upstream product

• 53-43-0 dehydroepiandrosterone 
• 51480-24-1 tetrahydropyranyloxypropargylmagnesium bromide 
• 63-05-8 Androstenedione 
• 55542-26-2 17,23-dihydroxy-21,24-dinor-17βH-chol-4-en-20-yn-3-one 

Downstream Products

• 976-70-5 3-oxopregn-4-ene-21,17α-carbolactone 
• 976-71-6 canrenone 

Relevant academic research and scientific papers

A spironolacton intermediate testosterone for synthesizing method

The invention relates to a synthesis method of a chemical medicine, and concretely relates to a synthesis method of a spironolactone intermediate testosterone lactone. The method is characterized in that a compound I 4-androstenedione (4AD) undergoes a two-step reaction of addition siloxane removal and oxidation cyclization to obtain the compound III testosterone lactone, and the reaction route is shown in the specification. Compared with traditional methods adopting a traditional raw material 16-dehydropregnenolone acetate with high price, the method provided by the invention adopting the cheap and easily available 4-androstenedione (4AD, I) as an initial raw material has extremely high production application and economic values under the affection of market supply and demand.

Having a method for the synthesis of intermediates spirondactone

The invention relates to a synthesis method of a chemical medicine, and concretely relates to a synthesis method of a spironolactone intermediate canrenone. The method comprises the following steps: carrying out an ethynylation reaction on a compound I 4-androstenedione (4AD), hydrogenating, carrying out an oxidation cyclization reaction, and carrying out a bromization and debromination reaction to obtain the compound V canrenone, and the above reaction route is shown in the specification. A synthesis method of the structure of an important 21,17-carboxy lactone spiro ring adopted in the invention is different from previous process modes, and is concise and efficient. The method has the characteristics of high yield, good selectivity, low cost, mild reactions, suitableness for industrialization, stability and easy realization.