55556-41-7Relevant academic research and scientific papers
Conformationally restricted homotryptamines 3. Indole tetrahydropyridines and cyclohexenylamines as selective serotonin reuptake inhibitors
Deskus, Jeffrey A.,Epperson, James R.,Sloan, Charles P.,Cipollina, Joseph A.,Dextraze, Pierre,Qian-Cutrone, Jingfang,Gao, Qi,Ma, Baoqing,Beno, Brett R.,Mattson, Gail K.,Molski, Thaddeus F.,Krause, Rudolph G.,Taber, Matthew T.,Lodge, Nicholas J.,Mattson, Ronald J.
, p. 3099 - 3104 (2008/02/13)
A series of indole tetrahydropyridine and indole cyclohexenylamines was prepared, and their binding affinities at the human serotonin transporter (SERT) were determined. In particular, a nitrile substituent at the C5 position of the indole ring gave poten
USE OF (3-(1-(3-PHENYL-PROPENYL)-PIPERIDIN-4-YL)-2,3-DIHYDRO-INDOL-1-YL)-(PYRIDIN-4-YL)-METHANONE DERIVATIVES AND RELATED COMPOUNDS AS INSECTICIDES
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Page/Page column 135, (2010/02/12)
The use of a compound of formula (I): R3 N Y R1(I) wherein Y is a single bond, C=O, C=S or S(O)71 where m is 0, 1 or 2; R1, R2 , R3 , R4, R8 and Ra are specified organ
5-HT1F agonists
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, (2008/06/13)
The present invention relates to a compound of formula (I): or a pharmaceutical acid addition salt thereof; which is useful for activating 5-HT1freceptors and inhibiting protein extravasation in a mammal.
BENZOMORPHAN RELATED COMPOUNDS. XXII. REDUCTION OF 3-(TETRAHYDROPYRIDYL)INDOLES TO INDOLINES. SYNTHESIS OF A NEW TYPE OF INDOLOMORPHAN
Bonjoch, Josep,Boncompte, Fontsanta,Casamitjana, Nuria,Bosch, Joan
, p. 6693 - 6702 (2007/10/02)
The first synthesis of an indolomorphan system has been achieved through a route involving the acid-catalyzed cyclization of a 3-(tetrahydro-2-pyridyl)indoline.A procedure for the reduction of 3-(tetrahydropyridyl)indoles to the corresponding indolines, consisting in the formation of the tetrahydropyridine-borane complex followed by treatment with ethanolic hydrochloric acid, is established.
Treating psychic disorders with tetrahydropyridin-4-yl-1H-indoles
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, (2008/06/13)
Novel antidepressant, antiemetic and neuroleptic compositions containing as the active ingredient at least one compound of the formula STR1 wherein R is selected from the group consisting of hydrogen and methoxy, R1 and R2 are individually selected from the group consisting of hydrogen and methyl and their non-toxic, pharmaceutically acceptable acid addition salts and a novel method of treating psychic disorders in warm-blooded animals.
