111963-87-2

Basic information

• Product Name: 5-METHOXY-3-(1-METHYL-4-PIPERIDINYL)INDOLE
• Synonyms: 5-METHOXY-3-(1-METHYL-4-PIPERIDINYL)INDOLE;5-methoxy-3-(1-methylpiperidin-4-yl)-1H-indole
• CAS NO: 111963-87-2
• Molecular Formula: C₁₅H₂₀N₂O
• Molecular Weight: 244.33
• Mol File: 111963-87-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 409.333 °C at 760 mmHg
• Flash Point: 201.358 °C
• Appearance: /
• Density: 1.12 g/cm³
• Vapor Pressure: 6.55E-07mmHg at 25°C
• Refractive Index: 1.601
• Storage Temp.: 2-8°C
• PKA: 16.77±0.30(Predicted)
• CAS DataBase Reference: 5-METHOXY-3-(1-METHYL-4-PIPERIDINYL)INDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHOXY-3-(1-METHYL-4-PIPERIDINYL)INDOLE(111963-87-2)
• EPA Substance Registry System: 5-METHOXY-3-(1-METHYL-4-PIPERIDINYL)INDOLE(111963-87-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 111963-87-2(Hazardous Substances Data)

Usage

General Description

5-Methoxy-3-(1-methyl-4-piperidinyl)indole is a chemical compound belonging to the class of compounds known as indoles. Indoles are compounds containing a cyclopenta[b]pyrrole ring system, which consists of a pyrrole ring fused to a benzene ring. 5-Methoxy-3-(1-methyl-4-piperidinyl)indole specifically has a methoxy group (-OCH3) and a N-methylpiperidine group attached to the indole core structure. 5-METHOXY-3-(1-METHYL-4-PIPERIDINYL)INDOLE has not been extensively studied and information about its potential uses, effects, toxicity, and safety is not widely available.

InChI:InChI=1/C15H20N2O/c1-17-7-5-11(6-8-17)14-10-16-15-4-3-12(18-2)9-13(14)15/h3-4,9-11,16H,5-8H2,1-2H3

Upstream product

• 13669-28-8 1-methyl-4-methylene-1-azacyclohexane 
• 201230-82-2 carbon monoxide 
• 3471-32-7 4-Methoxyphenylhydrazine 
• 1006-94-6 5-methoxylindole 
• 1445-73-4 1-Methyl-4-piperidone 
• 55556-41-7 5-methoxy-3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole 

Downstream Products

• 57477-39-1 5-hydroxy-3-(1-methylpiperidin-4-yl)indole 

Relevant articles and documents

BENZOMORPHAN RELATED COMPOUNDS. XXII. REDUCTION OF 3-(TETRAHYDROPYRIDYL)INDOLES TO INDOLINES. SYNTHESIS OF A NEW TYPE OF INDOLOMORPHAN

The first synthesis of an indolomorphan system has been achieved through a route involving the acid-catalyzed cyclization of a 3-(tetrahydro-2-pyridyl)indoline.A procedure for the reduction of 3-(tetrahydropyridyl)indoles to the corresponding indolines, consisting in the formation of the tetrahydropyridine-borane complex followed by treatment with ethanolic hydrochloric acid, is established.

5-HT1F agonists

The present invention relates to a compound of formula (I): or a pharmaceutical acid addition salt thereof; which is useful for activating 5-HT1freceptors and inhibiting protein extravasation in a mammal.