5556-22-9

Usage

Uses

Used in Pharmaceutical Synthesis:
3-Hydroxy-5-methyl-2-thiophenecarboxylic acid methyl ester is used as an intermediate in the synthesis of pharmaceuticals for its potential to contribute to the development of new drugs. Its unique structure allows it to be a versatile building block in medicinal chemistry, facilitating the creation of compounds with specific therapeutic targets.
Used in Agrochemical Production:
In the agrochemical industry, 3-Hydroxy-5-methyl-2-thiophenecarboxylic acid methyl ester is employed as a precursor in the production of various agrochemicals. Its properties make it suitable for the development of compounds that can be used in crop protection and pest management, enhancing agricultural productivity.
Used in Chemical Research:
3-Hydroxy-5-methyl-2-thiophenecarboxylic acid methyl ester serves as a valuable compound in chemical research, where it is used to study the properties and reactions of organic molecules. Researchers leverage its reactivity and structural features to explore new chemical pathways and mechanisms, contributing to the advancement of organic chemistry.
Used as a Building Block in Organic Synthesis:
Beyond its direct applications, 3-Hydroxy-5-methyl-2-thiophenecarboxylic acid methyl ester is utilized as a building block in organic synthesis. Its functional groups and structural attributes make it an ideal candidate for the construction of more complex organic molecules, which can be tailored for specific applications in various fields.

Upstream product

• 115049-10-0 3,3-bis-methoxycarbonylmethylsulfanyl-butyric acid methyl ester 
• 67525-85-3 3-Hydroxy-5-methyl-4,5-dihydro-thiophene-2-carboxylic acid methyl ester 
• 114821-96-4 3,3-bis-carboxymethylsulfanyl-butyric acid methyl ester 
• 74-93-1 methylthiol 
• 95201-94-8 methyl 2-chloro-3-oxo-2,3-dihydrothiophen-2-yl-carboxylate 
• 141-97-9 ethyl acetoacetate 
• 2365-48-2 Methyl thioglycolate 

Downstream Products

• 57245-91-7 3(5)-(hydrazidomethyl)-5(3)-methylpyrazole 
• 83261-26-1 3-methoxy-5-methylthiophene 2-carboxylic acid 
• 113589-58-5 4-Bromo-3-isopropoxy-5-methyl-thiophene-2-carboxylic acid 
• 113589-44-9 4-Bromo-3-ethoxy-5-methyl-thiophene-2-carboxylic acid methyl ester 
• 113589-59-6 3-Benzyloxy-4-bromo-5-methyl-thiophene-2-carboxylic acid 
• 113589-45-0 3-Benzyloxy-4-bromo-5-methyl-thiophene-2-carboxylic acid methyl ester 
• 113588-95-7 4-Bromo-3-(1-methylethoxy)-5-methyl-N-1 H-tetrazol-5-yl-2-thiophenecarboxamide 
• 113588-96-8 4-Bromo-3-benzyloxy-5-methyl-N-1 H-tetrazol-5-yl-2-thiophenecarboxamide 

Relevant academic research and scientific papers

Organic compounds and their use as pharmaceuticals

Compounds of the following formula have pharmacutical properties: STR1 in which R1 and R2 independently are hydrogen, halo, nitro, amino, C2-5 acylamino, C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, C1-4 alkylsulphonyl, N-substituted heterocyclyl, optionally substituted phenyl, optionally substituted phenylthio, optionally substituted phenylsulphonyl or optionally substituted phenylsulphonamido, or R1 and R2 together form a C3-5 alkylene bridge, R3 is C1-4 alkyl or C2-4 alkenyl, and X is (i) --(CH2)n N(R4)2 where each R4 independently is C1-4 alkyl, C2-4 alkenyl or optionally substituted C6 H5 CH2 --, and n is 1, 2 or 3, or (ii) a 5- to 8-membered alicyclic group containing one or two nitrogen atoms and directly attached to the amido nitrogen or attached by a C1-3 alkylene chain; and salts thereof.

N-1H-tetrazol-5-yl-2-thiophene carboxamides, N-1H-tetrazol-5-yl-2-pyrrole carboxamides, N-1H-tetrazol-5-yl-2-furan carboxamides, and anti-allergic and anti-inflammatory use thereof

The present invention is for compounds having the formula of N-1H-tetrazol-5-yl-2-thiophenecarboxamides, N-1H-tetrazol-5-yl-2-pyrrolecarboxamides, N-1H-tetrazol-5-yl-2-furancarboxamides or analogs of each of the carboxamides. The compounds are useful for the treatment of allergic or inflammatory conditions or diseases. Thus, pharmaceutical compositions and methods of use are also the invention. Processes of preparation for the compounds are also the invention.

Aromatization of Dihydrothiophenes. Thiophenesaccharin: A Sweet Surprise

Sulfuryl chloride has been shown to be highly effective in the dehydrogenation of 3,4-disubstituted-2,5-dihydrothiophenes and 2,3-disubstituted-4,5-dihydrothiophenes, in which the 3,4 and 2,3 substitutents are part of a β-keto carbonyl functionality or it

Thiophene compounds and their manufacture

New thiophene compounds and a new process for the manufacture of thiophene compounds by dehydrogenating dihydrothiophene with certain halogen compounds. The products are starting materials for the manufacture of pharmaceuticals, dyes and plant protection agents and, in particular, for the manufacture of additives to foodstuffs, feeds, beverages and pharmaceuticals.