57245-91-7 Usage
Molecular weight
140.14 g/mol
Structure
1H-Pyrazole-3-acetic acid, 5-methyl-, hydrazide is a heterocyclic compound that consists of a pyrazole ring (a five-membered ring with one nitrogen atom) and an acetic acid chain (a two-carbon chain with a carboxyl group). The 5-methyl substituent is attached to the pyrazole ring, and the hydrazide group (-NHNH2) is attached to the acetic acid chain.
Biological activity
1H-Pyrazole-3-acetic acid, 5-methyl-, hydrazide has potential biological activity due to its unique structure and reactivity. It is commonly used as a building block in the synthesis of various drugs and agrochemicals.
Synthesis
1H-Pyrazole-3-acetic acid, 5-methyl-, hydrazide is a hydrazide derivative of 1H-pyrazole-3-acetic acid, which can be synthesized through various chemical reactions.
Reactivity
The 5-methyl substituent on the pyrazole ring provides unique reactivity to 1H-Pyrazole-3-acetic acid, 5-methyl-, hydrazide, making it an important intermediate in the field of organic chemistry. Its specific properties and reactivity make it an important component in the design and synthesis of various biologically active compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 57245-91-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,2,4 and 5 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 57245-91:
(7*5)+(6*7)+(5*2)+(4*4)+(3*5)+(2*9)+(1*1)=137
137 % 10 = 7
So 57245-91-7 is a valid CAS Registry Number.
57245-91-7Relevant academic research and scientific papers
Cyclizations of monocyclic 5-nitropyridin-2(1H)-ones
Smolyar,Yutilov
experimental part, p. 1205 - 1210 (2009/08/07)
Reactions of 5-nitropyridin-2(1H)-one and its N-methyl derivative with hydrazine hydrate led to the formation of (1H-pyrazol-3-yl) acetohydrazide. Under analogous conditions, 1,3-dimethyl-5-nitropyridin2(1H)-one gave rise to 2-(1H-pyrazol-3-yl)propionohyd
6,12-Methanodipyrano[4,3-b:4,3-f]dioxocine-1,7-dione: The reactivity towards nitrogen nucleophiles
Svetlik, Jan,Hanus, Vladimir,Lagoja, Irene M.,Schantl, Joachim G.
, p. 1833 - 1838 (2007/10/03)
The reaction of the title compound (1) with hydrazine hydrate induces a complex ring transformation affording 3,4,6-trimethyl-1H-indazole-7-carboxylic acid (2) and (3-methyl-1H-pyrazol-5-yl)acetic acid hydrazide (3). The product structures have been elucidated by 2D-NMR techniques, and a mechanistic rationalization of this multistep reaction is presented. Methylhydrazine converts compound (1) into (1,3-dimethyl-1H-pyrazol-5-yl)acetic acid (12), while phenyl hydrazine fails to affect 1.
