5558-63-4Relevant academic research and scientific papers
Arylthio-metal exchange of α-arylthioalkanenitriles
Nath, Dinesh,Skilbeck, Melanie C.,Coldham, Iain,Fleming, Fraser F.
supporting information, p. 62 - 65 (2014/01/23)
The addition of BuLi, Bu3MgLi, Et2ZnBuLi, or Me 2CuLi to α-arylthioalkanenitriles triggers an arylthio-metal exchange. NMR spectroscopic analyses implicate organometallic attack on sulfur forming a three-coordinate sulfidate as the key intermediate. Electrophilic trapping affords tertiary and quaternary nitriles in high yield. The method addresses the challenge of improving the functional group tolerance and preventing polyalkylations.
Herbicide compositions containing a nitrile derivative as antidote
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, (2008/06/13)
The invention relates to a herbicide composition comprising as herbicidally active ingredient an urea derivative and/or a thiolcargamate derivative and/or a chloroacetanilide derivative together with a nitrile derivative of the general formula (I), STR1 wherein R1 and R2 which are the same or different, stand for hydroger, halogen or a methyl, ethyl, allyl, vinyl, phenyl or benzyl group; or R1 and R2 together may stand for a benzylidene group; and R3 means chlorine or a methyl, phenyl, chlorophenyl, alkoxyphenyl, chlorophenylamino, anilino, anilinomethylene, N-alkylanilinomethylene, N,N-dialkylanilinomethylene, alkoxyanilinomethylene, benzylaminomethylene, cyclohexylaminomethylene, N-alkyl-cyclohexylaminomethylene, hexamethyleniminomethylene, phthalimidomethylene, nitrophthalimidomethylene, morpholinomethylene, piperidinomethylene, C1-3 alkylaminomethylene, allylaminomethylene or di(C1-3 alkyl)aminorethylene group and/or together with a cyanopyridine and/or with a benzonitrile derivative optionally mono- or polysubstituted by halogen(s) or C1-3 alkoxy group(s) as antidote(s) in a mass ratio from 40:1 to 1:1 of the herbicidally active ingredient to the antidote nitrile derivative.
THE REDUCTIVE LITHIATION OF THIOACETALS, α,α-BIS(TRIMETHYLSILYL)-ALKYL SULFIDES, AND 2-ALKYL-2-ETHYLTHIOALKANENITRILES USING TRIBUTYLSTANNYLLITHIUM
Takeda, Takeshi,Ando, Kazuo,Mamada, Akira,Fujiwara, Tooru
, p. 1149 - 1152 (2007/10/02)
The reaction of thioacetals of phenyl ketones, α,α-bis(trimethylsilyl)alkyl sulfides, and 2-alkyl-2-ethylthioalkanenitriles with tributhylstannyllithium gave the corresponding α-anions of sulfides, α,α-bis(trimethylsilyl)alkane, and nitriles, respectively.
PHASE TRANSFER CATALYSIS USING CHIRAL CATALYSTS. V. ASYMMETRIC NUCLEOPHILIC SUBSTITUTIONS WITH C, O, N AND S-ANIONS
Julia, S.,Ginebreda, A.,Guixer, J.,Tomas, A.
, p. 3709 - 3712 (2007/10/02)
Several asymmetric nucleophilic substitutions with C, N, O and S-anions have been performed under PTC conditions using chiral quaternary ammonium salts as PT catalysts.
