556039-33-9

Upstream product

• 26260-02-6 2-iodobenzaldehyde 
• 556039-60-2 methyl N-(4-benzyloxy-2-bromo-3,5-dimethoxy)-N-(4-methoxybenzyl)carbamate 
• 556039-57-7 N-(4-benzyloxy-2-bromo-3,5-dimethoxy)-N-(4-methoxybenzyl)amine 
• 137214-62-1 4-(benzyloxy)-2-bromo-3,5-dimethoxybenzaldehyde 
• 2393-23-9 4-methoxy-benzylamine 

Relevant academic research and scientific papers

A short total synthesis of the alkaloids piperolactam C, goniopedaline, and stigmalactam

The total synthesis of the polyalkoxylated alkaloids piperolactam C, goniopedaline and stigmalactam by combinatorial metalation/cyclization strategies has been achieved. The synthetic route involved the preliminary construction of the polyalkoxylated isoindolinone template by Parham's technique. Benzylic lactam deprotonation allowed connection of a hydroxybenzyl appendage, and the synthesis of the target natural products was completed by subsequent E1cB elimination, radical cyclization and final deprotection. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.