55605-86-2Relevant academic research and scientific papers
Monofluorination of fluorinated ethers with high-valency metal fluorides
Kurosawa, Shigeru,Arimura, Takashi,Sekiya, Akira
, p. 111 - 114 (1997)
Fluorinated ethers were fluorinated by high-valency metal fluorides such as MnF3, CoF3, and KCoF4. The monofluorinating reactivities of these reagents with 2,2,2-trifluoroethyl difluoromethyl ether, bis(2,2,2-trifluoroethyl) ether, and 2-chloro-1, 1,2-trifluoroethyl methyl ether follow the order MnF3 > CoF3 > KCoF4. The order of monofluorination reactivity with fluorinated ethers did not agree with that of gemdifluorohydrofluorocarbons (CoF3 > MnF3 > KCoF4). Regioselective monofluorination of 2,2,2-trifluoroethoxy compounds with MnF3 was achieved at the methylene position adjacent to the trifluoromethyl group.
