55606-33-2Relevant academic research and scientific papers
Regio- and Enantioselective Formal Hydroamination of Enamines for the Synthesis of 1,2-Diamines
Yu, Lu,Somfai, Peter
supporting information, p. 8551 - 8555 (2019/05/21)
The asymmetric formal hydroamination of enamines using a CuH catalyst is reported. The method provides a straightforward and efficient approach to the synthesis of chiral 1,2-dialkyl amines in good yields with high levels of enantioselectivities for a broad range of substrates, and should have significant value for the preparation of molecules bearing a 1,2-diamine motif.
Cycloaddition of nitrones with arynes generated from benzobisoxadisilole or 2,3-naphthoxadisilole
Wu, Kaicheng,Chen, Yali,Lin, Yibei,Cao, Weiguo,Zhang, Min,Chen, Jie,Lee, Albert W.M.
experimental part, p. 578 - 582 (2010/09/05)
1,3-Dipolar cycloaddition of nitrones with arynes generated in situ from benzobisoxadisilole or 2,3-naphthoxadisilole afforded the oxadisilole fused benzo[d]isoxazoline or the naphtho[2,3-d]isoxazoline derivatives at room temperature in good yields.
The Reaction between Cyanide Ion and Nitrones; a Novel Imidazole Synthesis
Cawkill, Eric,Clark, Nigel G.
, p. 244 - 248 (2007/10/02)
By contrast with the CN-diphenylnitrones, cold aqueous ethanolic potassium cyanide converts N-methyl-C-phenylnitrone into 1-methyl-4,5-diphenylimidazole.The scope of this reaction has been investigated, and shown to proceed via intermediate cyano-imines, some of which have been synthesised by alternative routes.
