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5-methyl-pyridine-2-sulfonic acid [6-chloro-5-(2-methoxy-phenoxy)-2-(3,4,5-trimethoxy-phenyl)-pyrimidin-4-yl]-amide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

556066-76-3

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556066-76-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 556066-76-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,5,6,0,6 and 6 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 556066-76:
(8*5)+(7*5)+(6*6)+(5*0)+(4*6)+(3*6)+(2*7)+(1*6)=173
173 % 10 = 3
So 556066-76-3 is a valid CAS Registry Number.

556066-76-3Upstream product

556066-76-3Relevant academic research and scientific papers

Bis-sulfonamides as endothelin receptor antagonists

Boss, Christoph,Bolli, Martin H.,Weller, Thomas,Fischli, Walter,Clozel, Martine

, p. 951 - 954 (2003)

Modification of the structure of bosentan 1, the first marketed endothelin receptor antagonist (Tracleer), by introduction of a second sulfonamide function at the alkoxy side chain, led to bis-sulfonamides 2. This allowed to prepare dual ETA/ETB as well as ETB receptor selective antagonists, which could serve as tools to investigate the pharmacological consequences of selective ETB receptor blockade.

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