55654-03-0

Basic information

• Product Name: 3-benzyl-1,2,4-oxadiazol-5-amine
• Synonyms: 3-benzyl-1,2,4-oxadiazol-5-amine
• CAS NO: 55654-03-0
• Molecular Weight: 0
• Mol File: 55654-03-0.mol

Chemical Properties

• CAS DataBase Reference: 3-benzyl-1,2,4-oxadiazol-5-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-1,2,4-oxadiazol-5-amine(55654-03-0)
• EPA Substance Registry System: 3-benzyl-1,2,4-oxadiazol-5-amine(55654-03-0)

Safety Data

• Hazardous Substances Data: 55654-03-0(Hazardous Substances Data)

Upstream product

• 506-68-3 bromocyane 
• 19227-11-3 N'-hydroxy-2-phenylethanimidamide 
• 19227-11-3 N-hydroxy-2-phenylethanimidamide 
• 140-29-4 phenylacetonitrile 
• 1823-00-3 3-benzyl-5-trichloromethyl-[1,2,4]oxadiazole 

Downstream Products

• 60776-10-5 5-amino-α-phenyl-1,2,4-oxadiazole-3-acetic acid 

Relevant articles and documents

DERIVATIVES OF OXADIAZOLE AND PYRIDAZINE, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS

The invention relates to compounds of formula (I): in which: n is equal to 0 or 1; D represents an oxygen atom or a bond; W represents a nitrogen atom or a —CH— group; X1 represents a nitrogen atom or a —CH═CH— group; X2 represents an oxygen atom or a nitrogen atom; X3 represents an oxygen atom or a nitrogen atom; one of X1, X2, X3 being other than a nitrogen atom, X2 and X3 not being an oxygen atom at the same time; R1, R2 are absent or represent, (i) independently of one another, a hydrogen atom or a (C1-C4)alkyl group, (ii) R1 and R2 may form, with the carbon atom to which they are attached, a —(C3-C10)cycloalkyl- group; Y represents a —(C3-C10)cycloalkyl-, aryl or aryloxy group, said groups being optionally substituted with one or more substituents chosen from a halogen atom or a (C1-C6)alkoxy group; Z1 is absent or represents an —NH— function; Z2 and Z3 are as defined in the description. The invention also relates to a process for preparing compounds of formula (I), compositions containing them and their application in therapeutics.

DERIVATIVES OF OXADIAZOLE AND PYRIDAZINE, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS

The invention relates to compounds of formula (I): in which: n is equal to 0 or 1; D represents an oxygen atom or a bond; W represents a nitrogen atom or a -CH- group; X1 represents a nitrogen atom or a -CH=CH- group; X2 represents an oxygen atom or a nitrogen atom; X3 represents an oxygen atom or a nitrogen atom; one of X1, X2, X3 being other than a nitrogen atom, X2 and X3 not being an oxygen atom at the same time; R1, R2 are absent or represent, (i) independently of one another, a hydrogen atom or a (C1 -C4)alkyl group, (ii) R1 and R2 may form, with the carbon atom to which they are attached, a -(C3-C10)cycloalkyl- group; Y represents a -(C3-C10)cycloalkyl-, aryl or aryloxy group, said groups being optionally substituted with one or more substituents chosen from a halogen atom or a (C1 -C6)alkoxy group; Z1 is absent or represents an -NH- function; Z2 and Z3 are as defined in the description. The invention also relates to a process for preparing compounds of formula (I), compositions containing them and their application in therapeutics.

Amino-1,2,4-oxadiazolyl-3-acetyl cephalosporins

Amino-1,2,4-oxadiazolyl-3-acetyl penicillins and cephalosporins of the general formula SPC1 Wherein A is either SPC2 R1 and R2 are independently selected from hydrogen and lower alkyl or R1 and R2 together with