55655-84-0 Usage
Uses
Used in Pharmaceutical Industry:
1-(3-TRIFLUOROMETHYL-PHENYL)-BUTANE-1,3-DIONE is used as a key reagent for the synthesis of various pharmaceuticals. Its electron-withdrawing trifluoromethyl group enhances the reactivity and selectivity of the molecule, making it a valuable building block in the creation of new drugs with improved efficacy and safety profiles.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(3-TRIFLUOROMETHYL-PHENYL)-BUTANE-1,3-DIONE serves as an essential intermediate in the production of agrochemicals. Its unique structure contributes to the development of novel compounds with enhanced pesticidal properties, aiming to increase crop yield and protect against various pests and diseases.
Used in Organic Synthesis:
1-(3-TRIFLUOROMETHYL-PHENYL)-BUTANE-1,3-DIONE is utilized as a versatile building block in organic synthesis. Its strong electron-withdrawing nature allows for a wide range of chemical reactions, facilitating the creation of diverse chemical compounds with potential applications in various industries, including materials science and specialty chemicals.
Used in Material Science:
1-(3-TRIFLUOROMETHYL-PHENYL)-BUTANE-1,3-DIONE is also used in the field of material science as a component in the development of new materials. The unique properties conferred by the trifluoromethyl group can lead to the creation of materials with improved characteristics, such as enhanced stability, reactivity, or selectivity, which can be beneficial in various technological applications.
Check Digit Verification of cas no
The CAS Registry Mumber 55655-84-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,6,5 and 5 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 55655-84:
(7*5)+(6*5)+(5*6)+(4*5)+(3*5)+(2*8)+(1*4)=150
150 % 10 = 0
So 55655-84-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H9F3O2/c1-7(15)5-10(16)8-3-2-4-9(6-8)11(12,13)14/h2-4,6H,5H2,1H3
55655-84-0Relevant academic research and scientific papers
2-(1H-Pyrazol-1-yl)acetic acids as chemoattractant receptor-homologous molecule expressed on Th2 lymphocytes (CRTh2) antagonists
Andrés, Miriam,Bravo, Mónica,Buil, Maria Antonia,Calbet, Marta,Castillo, Marcos,Castro, Jordi,Eichhorn, Peter,Ferrer, Manel,Lehner, Martin D.,Moreno, Imma,Roberts, Richard S.,Sevilla, Sara
, p. 168 - 184 (2014/01/06)
In this manuscript, the synthesis and biological activity of a series of pyrazole acetic acid derivatives as CRTh2 antagonists is presented. Biological evaluation in vitro revealed that the pyrazole core showed in several cases a different structure-activity relationship (SAR) to that of related indole acetic acid. A potent series of ortho-sulfonyl benzyl substituents was found, from which compounds 27 and 63 were advanced to in vivo profiling.
Direct route to 1,3-diketones by palladium-catalyzed carbonylative coupling of aryl halides with acetylacetone
Korsager, Signe,Nielsen, Dennis U.,Taaning, Rolf H.,Lindhardt, Anders T.,Skrydstrup, Troels
supporting information, p. 17687 - 17691 (2014/01/17)
Man up your magnesium! By employing a MgCl2/Et3N system, aryl diketones can be generated from the Pd-catalyzed carbonylative α-arylation of acetylacetone with aryl bromides (see scheme). The method is ideal for the introduction of carbon isotopes into more complex structures, since only stoichiometric amounts of carbon monoxide are employed. Copyright
Formation of functionalized 2H-azirines through phio-mediated trifluoroethoxylation and azirination of enamines
Sun, Xiaoqian,Lyu, Youran,Zhang-Negrerie, Daisy,Du, Yunfei,Zhao, Kang
supporting information, p. 6222 - 6225 (2014/01/17)
A variety of enaminones and enamine carboxylic esters were converted to trifluoroethoxylated 2H-azirines through reactions with PhIO in trifluoroethanol (TFE). The cascade reaction is postulated to proceed via a PhIO-mediated oxidative trifluoroethoxylation and a subsequent azirination of the α-trifluoroethoxylated enamine intermediates.
