55656-25-2

Basic information

• Product Name: 5-Methyloxazolo[4,5-b]pyridin-2(3H)-one
• Synonyms: 5-Methyloxazolo[4,5-b]pyridin-2(3H)-one;5-Methyl-3H-oxazolo[4,5-b]pyridin-2-one
• CAS NO: 55656-25-2
• Molecular Formula: C₇H₆N₂O₂
• Molecular Weight: 150.13474
• Mol File: 55656-25-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.345g/cm³
• Refractive Index: 1.581
• CAS DataBase Reference: 5-Methyloxazolo[4,5-b]pyridin-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methyloxazolo[4,5-b]pyridin-2(3H)-one(55656-25-2)
• EPA Substance Registry System: 5-Methyloxazolo[4,5-b]pyridin-2(3H)-one(55656-25-2)

Safety Data

• Hazardous Substances Data: 55656-25-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H6N2O2/c1-4-2-3-5-6(8-4)9-7(10)11-5/h2-3H,1H3,(H,8,9,10)

Upstream product

• 20348-16-7 2-amino-3-hydroxy-6-methylpyridine 
• 530-62-1 1,1'-carbonyldiimidazole 

Downstream Products

• 1092569-08-8 tert-butyl 4-{2-[3-(5-methyl-2-oxooxazolo[4,5-b]pyridin-3-ylmethyl)phenyl]-pyrimidin-4-yl}piperazine-1-carboxylate 
• 1092569-00-0 tert-butyl 4-{2-[3-(5-methyl-2-oxooxazolo[4,5-b]pyridin-3-ylmethyl)phenyl]pyrimidin-5-yl}piperazine-1-carboxylate 
• 1092568-12-1 5-methyl-3-{3-[5-(4-methylpiperazin-1-yl)pyrimidin-2-yl]-benzyl}-3H-oxazolo[4,5-b]pyridin-2-one 
• 1092568-37-0 3-(4-methylpiperazin-1-yl)propyl [3-(5-methyl-2-oxooxazolo-[4,5-b]pyridin-3-ylmethyl)phenyl]carbamate 
• 1092568-91-6 3-[3-(5-bromopyrimidin-2-yl)benzyl]-5-methyl-3H-oxazolo-[4,5-b]pyridin-2-one 
• 134337-07-8 5-methyl-3-<2-(4-phenyl-1-piperazinyl)ethyl>oxazolo<4,5-b>pyridin-2(3H)-one 

Relevant articles and documents

2-OXO-3-BENZYLBENZOXAZOL-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS MET KINASE INHIBITORS FOR THE TREATMENT OF TUMOURS

Compounds of the formula (I), in which R1, R2, R3, R3′, R4, R4′, E, E′, E″ and E′″ have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.

Medicinal oxazolopyridine compounds

Compounds of general formula (I): STR1 in which: R1 and R2 each represent a hydrogen atom or, with the nitrogen and oxygen which bear them, form an --O--CO--N link, W represents a halogen atom or a lower alkyl or alkoxy group optionally substituted with one or more halogen atoms, such as trifluoromethyl, and m being between 0 and 3, A is a linear or branched alkyl radical comprising from 1 to 6 carbon atoms, R3 and R4 are defined in the description have medicinal properties.