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Imidazo[1,2-a]pyrimidin-5(1H)-one, also known as N^2-hydroxyimino-N^2-methylimidazolidine, is a heterocyclic chemical compound with the molecular formula C5H6N4O. It features a fused imidazole and pyrimidine ring system and is characterized by its white to off-white solid appearance. Imidazo[1,2-a]pyrimidin-5(1H)-one possesses a range of biological activities and is recognized for its potential pharmaceutical applications, particularly in drug development. It also serves as a reagent and intermediate in organic synthesis.

55662-68-5

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55662-68-5 Usage

Uses

Used in Pharmaceutical Development:
Imidazo[1,2-a]pyrimidin-5(1H)-one is utilized as a key component in the development of new pharmaceuticals due to its diverse chemical and biological properties. Its potential applications in medicine are currently being explored, highlighting its importance in the field of drug discovery and design.
Used as a Reagent and Intermediate in Organic Synthesis:
In the realm of organic chemistry, Imidazo[1,2-a]pyrimidin-5(1H)-one serves as a valuable reagent and intermediate. This role is crucial for the synthesis of various complex organic compounds, contributing to the advancement of chemical research and the creation of novel chemical entities.
Used in Cancer Therapy Research:
Imidazo[1,2-a]pyrimidin-5(1H)-one has demonstrated potential in the field of cancer therapy. It is being actively investigated for its antitumor effects, with the aim of identifying its role in the development of future cancer treatments.
Used in Anti-Inflammatory and Antioxidant Applications:
The biological activities of Imidazo[1,2-a]pyrimidin-5(1H)-one extend to anti-inflammatory and antioxidant properties. These characteristics make it a candidate for use in treatments targeting inflammation and oxidative stress-related conditions, further expanding its potential uses in healthcare.

Check Digit Verification of cas no

The CAS Registry Mumber 55662-68-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,6,6 and 2 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 55662-68:
(7*5)+(6*5)+(5*6)+(4*6)+(3*2)+(2*6)+(1*8)=145
145 % 10 = 5
So 55662-68-5 is a valid CAS Registry Number.

55662-68-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 5H,8H-Imidazo[1,2-a]pyrimidin-5-one

1.2 Other means of identification

Product number -
Other names Imidazo<1,2-a>pyrimidin-2-aethylacetat

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:55662-68-5 SDS

55662-68-5Relevant academic research and scientific papers

Facile unmasking of ethenylated isocytosines via diacetoxylation with lead tetraacetate

Sako,Totani,Hirota,Maki

, p. 235 - 237 (2007/10/02)

Treatment of ethenylated isocytosines, imidazolo[1,2-a]pyrimidine-5(1H)-one (2) and -7(8H)-one (3), with lead tetraacetate (LTA) in glacial acetic acid followed by alkaline hydrolysis resulted in the smooth removal of the ethenyl group to give isocytosine (1) in high yields. The unmasking of 2 by LTA to 1 was compared with the results using iodosylbenzene diacetate and N-bromosuccinimide.

Structural Alteration of Nucleic Acid Bases by Bromomalonaldehyde

Nair, Vasu,Offerman, Rick J.,Turner, Gregory A.

, p. 4021 - 4025 (2007/10/02)

Bromomalonaldehyde (BMDA), prepared by bromination of malonaldehyde with elemental bromine, has been employed to modify a number of nucleic acid bases.These reactions transform pyrimidine and purine bases into modified systems containing etheno and etheno carboxaldehyde moieties, among other products.The structures of these modified bases were established by UV, mass spectral, and high-field NMR data.Fluorescence emission data for some of the adducts are of significance.The general mechanism of modification is discussed.

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