5568-33-2Relevant articles and documents
NITROGEN HETEROCYCLIC COMPOUNDS AND METHODS OF USE
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Paragraph 1808; 2031, (2021/06/26)
The present disclosure relates to compounds of formula (I): and pharmaceutically acceptable salts and stereoisomers thereof. The present disclosure also relates to methods of preparing the compounds, compositions comprising the compounds, and methods of using the compounds as inhibitors of receptor tyrosine kinases, in particular oncogenic mutants of ErbB-receptors e.g. in the treatment of cancer.
Facile, environmentally friendly synthesis of benzaldehyde and phenylacetaldehyde analogs from readily available toluene derivatives
Dai, Liyan,Yu, Jie,Chen, Yingqi,Yu, Shichao
, p. 3078 - 3084 (2011/09/14)
A facile environmentally friendly synthesis of bezaldehyde and phenylacetaldehyde analogs from readily available toluene derivatives is described. Oxidation of the styrylamines by H2O2 H2O2 affords benzaldehydes in moderate yields, while the hydrolysis of styrylamines afforded phenylacetaldehyde analogs in good yields. Copyright
BENZOFUROPYRIMIDINONES AS PROTEIN KINASE INHIBITORS
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Page/Page column 207-208, (2009/08/14)
A compound according to formula I: or a pharmaceutically acceptable salt thereof; wherein R1, R2, R3a, R3b, R3c and R3d are as defined in the specification, pharmaceutical compositions thereof, and methods of use thereof.