77455-54-0

Usage

Uses

Used in Chemical Synthesis:
(2-chloro-4-nitrophenyl)methanediyl diacetate is used as an intermediate in the chemical synthesis industry for the production of other organic compounds. Its unique structure allows it to be a versatile building block in the creation of various chemical products.
Used in Pharmaceutical Manufacturing:
In the pharmaceutical industry, (2-chloro-4-nitrophenyl)methanediyl diacetate is used as an intermediate in the manufacturing of pharmaceuticals. Its reactivity and functional groups make it a valuable component in the development of new drugs and medications.
It is important to handle (2-chloro-4-nitrophenyl)methanediyl diacetate with care, as it may be harmful if swallowed, inhaled, or if it comes into contact with the skin. Proper safety measures should be taken during its use and disposal to minimize any potential risks.

Upstream product

• 121-86-8 2-chloro-4-nitrotoluene 
• 108-24-7 acetic anhydride 

Downstream Products

• 77455-67-5 (E)-α,α',2,2'-tetrachloro-4,4'-dinitrostilbene 
• 77455-66-4 (Z)-α,α',2,2'-tetrachloro-4,4'-dinitrostilbene 
• 77455-68-6 2,2'-dichloro-4,4'-dinitrodiphenylacetylene 
• 77455-65-3 3-chloro-4-(dichloromethyl)-1-nitrobenzene 
• 73097-02-6 ethyl 2-chloro-4-nitrobenzoate 
• 198821-76-0 3-chloro-4-(oxazol-5-yl)phenylamine 
• 5568-33-2 2-chloro-4-nitrobenzaldehyde 

Relevant academic research and scientific papers

Synthesis, larvicidal activity, and SAR studies of new benzoylphenylureas containing oxime ether and oxime ester group

A series of new structural benzoylphenylureas (BPUs) containing oxime ether and oxime ester group were designed and synthesized. The larvicidal activities against Oriental armyworm and mosquito of these benzoylphenylureas were evaluated and the result of bioassay displayed specific structure-activity relationship (SAR). Most of the compounds exhibited excellent larvicidal activities against Oriental armyworm and mosquito. Interestingly, some compounds showed different structure-activity relationship towards diamondback moth, beet armyworm, and corn borer although three tested insects all belong to the same insect order.

Inhibitors of inosine monophosphate dehydrogenase: SARs about the N-[3-methoxy-4-(5-oxazolyl)phenyl moiety

The first reported structure-activity relationships (SARs) about the N-[3-methoxy-4-(5-oxazolyl)phenyl moiety for a series of recently disclosed inosine monophosphate dehydrogenase (IMPDH) inhibitors are described. The syntheses and in vitro inhibitory values for IMPDH II, and T-cell proliferation (for select analogues) are given.

Novel diamide-based inhibitors of IMPDH

A series of novel amide-based small molecule inhibitors of inosine monophosphate dehydrogenase is described. The synthesis and the structure-activity relationships (SARs) derived from in vitro studies are presented.

Inhibitors of IMPDH enzyme

The present invention relates to a novel class of compounds which are IMPDH inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting IMPDH enzyme activity and consequently, may be advantageously used as therapeutic agents for IMPDH mediated processes. This invention also relates to methods for inhibiting the activity of IMPDH using the compounds of this invention and related compounds.

Organic nonlinear optical material

The present invention provides an organic nonlinear optical material including a benzylidene-aniline derivative having an electron-donating substituent introduced at the 4-position and an electron-accepting substituent introduced at the 4'-position, by se

Comparative Reactivity of Substituted 4-Nitrobenzylidene Dichlorides with Alkali

A comparative study of the reactions of substituted 4-nitrobenzylidene dichlorides ArCHCl2 (Ar = 3-Cl-4-NO2C6H3, 2-Cl-4-NO2C6H3, 4-NO2C6H4, 3,5-Me2-4-NO2C6H2, and 2-Me-4-NO2C6H3) with aqueous alcoholic alkali shows that chlorine substitution enhances the