55703-70-3

Upstream product

• 1458-98-6 2-methyl-3-bromo-1-propene 
• 19520-74-2 3-hydroxy-5-methoxy-benzoic acid methyl ester 
• 563-47-3 3-Chloro-2-methylpropene 
• 19520-75-3 3-hydroxy-5-methoxybenzoic acid 

Downstream Products

• 55104-56-8 3,4-dihydro-5-hydroxy-7-methoxy-3,3-dimethyl-1H-2-benzopyran-1-one 
• 81184-29-4 3-hydroxy-5-methoxy-2-(2-methylallyl)benzoic acid 
• 81184-28-3 methyl 2,3-dihydro-6-methoxy-2,2-dimethyl-4-benzofurancarboxylate 

Relevant academic research and scientific papers

Ruthenium-Catalyzed Hydroarylation and One-Pot Twofold Unsymmetrical C?H Functionalization of Arenes

A methyl phenyl sulfoximine (MPS) is used as a directing group in the ruthenium-catalyzed intramolecular hydroarylation of alkene-tethered benzoic acid derivatives to afford dihydrobenzofurans and indolines in good to excellent yields. A one-pot, unsymmetrical, twofold C?H functionalization involving intramolecular C?C and intermolecular C?C/C?N bond formations is successfully demonstrated by using a single set of catalytic reaction conditions, which is unprecedented thus far. A novel isoquinolone-bearing dihydrobenzofuran is constructed through an unsymmetrical twofold C?H functionalization.

SYNTHESIS OF 4-ALKENYL-3,5-DIMETHOXYBENZOIC ACIDS BY CLAISEN REARRANGEMENT

Methyl 3-allyloxy-5-methoxybenzoate (1a) and its methyl homologues on the α, β and γ carbon atoms (1b,c,d) have been subjected to Claisen rearrangement.The structures of the rearranged products have been determined and the factors affecting the isomeric r