55705-10-7

Upstream product

• 151-50-8 potassium cyanide 
• 98-88-4 benzoyl chloride 
• 105-07-7 4-cyanobenzaldehyde 
• 613-90-1 benzoyl cyanide 

Downstream Products

• 89549-84-8 Benzoic acid cyano-(4-cyano-phenyl)-(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-methyl ester 
• 89549-56-4 4-(1-Phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-carbonyl)-benzonitrile 
• 102034-63-9 2-benzoyloxy-1,2-bis(4-cyanophenyl)ethanone 

Relevant academic research and scientific papers

DABCO-Mediated Synthesis and Biological Activity of Cyanihydrin Esters

Cyanohydrin esters 1-31 have been prepared from α-ketonitriles and aldehydes using DABCO (1,4-diazabicyclooctane) as nucleophilic acylation catalyst.The modofied piperonal 8 was found to inhibit the formation of thromboxane synthetase.

CYANOHYDRINS AS SUBSTRATES IN BENZOIN CONDENSATION. REGIOCONTROLLED MIXED BENZOIN CONDENSATION

O-Benzoylated cyanohydrins of aromatic aldehydes have been used as one of the substrates in the benzoin condensation.They were treated with aromatic aldehydes under phase-transfer conditions to result in benzoin benzoates.By this method aldehydes which fail to undergo condensation using traditional conditions could be converted into benzoins.By the Umpolung of reactivity of the pertinent aldehyde it was possible to prepare both isomeric unsymmetrical benzoins, including the thermodynamically less stable ones.

Studies on Pyrazolopyrimidine Derivatives. XIII. Aryl Migration of 4-Aroyl-1H-pyrazolopyrimidines to 4-Aryl-4,5-dihydro-1H-pyrazolopyrimidine-4-carboxylic Acids

When a mixture of 4-aroyl-1-phenyl-1H-pyrazolopyrimidines (3) and sodium hydroxide in dimethyl sulfoxide (DMSO) was stirred for 1 h at room temperature, migration of the aryl group to the 4-position occurred, i.e., the benzilic acid rearrangement,