55718-52-0

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 57-13-6 urea 

Downstream Products

• 1207548-58-0 5-(4-bromophenyl)-4-(4-chlorophenyl)-6-p-tolyl-3,4-dihydropyrimidin-2(1H)-one 
• 1207548-50-2 5-(4-bromophenyl)-4,6-bis(4-chlorophenyl)-3,4-dihydropyrimidin-2(1H)-one 
• 1207548-62-6 4-(4-chlorophenyl)-5-phenyl-6-p-tolyl-3,4-dihydropyrimidin-2(1H)-one 
• 1262142-62-0 4-(4-chlorophenyl)-2-oxo-N-(pyridin-2-yl)-1,2,3,4-tetrahydroquinazoline-6-sulfonamide 
• 1262142-56-2 4-(4-chlorophenyl)-6-methyl-3,4-dihydroquinazolin-2(1H)-one 
• 1262142-52-8 4-(4-chlorophenyl)-2-oxo-1,2,3,4-tetrahydroquinazoline-6-carboxylic acid 
• 136203-56-0 9-(4-Chloro-phenyl)-3,3,6,6-tetramethyl-3,4,6,7-tetrahydro-2H,5H-acridine-1,8-dione 
• 136203-53-7 9-(4-chlorophenyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydro-2H,5H-1,8-acridinedione 
• 1207548-54-6 5-(4-bromophenyl)-4-(4-chlorophenyl)-6-phenyl-3,4-dihydropyrimidin-2(1H)-one 
• 1198151-50-6 3,4-dihydro-4-(4-chlorophenyl)-5,6-diphenylpyrimidin-2-(1H)-one 
• 92550-15-7 N,N'-bis(4-chlorobenzyl)urea 
• 5948-71-0 4-(4-chlorophenyl)-5-(ethoxycarbonyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one 

Relevant academic research and scientific papers

An efficient synthesis of 4,5-diaryl-3,4-dihydropyrimidin-2(1: H)-one via a cesium carbonate-promoted direct condensation of 1-aryl-2-propanone with 1,1'-(arylmethylene)diurea

An efficient method for the synthesis of 4,5-diaryl-3,4-dihydropyrimidin-2(1H)-one by using 1,1'-(arylmethylene)diurea and 1-aryl-2-propanone as substrates was developed. The reactions proceeded efficiently in the presence of Cs2CO3 to give the desired pr

Biginelli reaction via bis-ureide intermediate in low melting mixture

This paper deals with the study of mechanism of the Biginelli reaction using low melting mixture as solvent and catalyst. The catalytic effect of low melting mixture and the reaction mechanism is discussed on the basis of nuclear magnetic resonance (NMR)

Nanosilica-bonded N-(propylsulfonyl) piperazine-N-sulfamic acid as recyclable catalyst for synthesis of 1,1′-(arylmethylene) diureas and 1,3,5-triazinane-2,4-dithiones

Nanosilica-bonded N-(propylsulfonyl) piperazine-N-sulfamic acid was easily prepared by functionalizing silica nanoparticles and characterized by thermogravimetric analysis, scanning electron microscopy, infrared (IR) spectroscopy, elemental analyses, and

Eco-efficiency and scalable synthesis of bisamides in deep eutectic solvent

Solvents define a major part of the environmental performance of processes in chemical industry and also impact on cost, safety and health issues. In order to minimize the environmental impact resulting from the use of volatile organic solvents in chemica

Synthesis and antitumor activity of some 2, 3-disubstituted quinazolin-4(3H)-ones and 4, 6- disubstituted- 1, 2, 3, 4-tetrahydroquinazolin- 2H-ones

The synthesis of some new 3-substituted quinazolin-4(3H)-ones and 3,4-dihydro-quinazolin-2(1H)-one derivatives and their biological evaluation as antitumor agents using the National Cancer Institute (NCI), disease oriented antitumor screening protocol are

Bronsted base-catalyzed one-pot three-component Biginelli-type reaction: An efficient synthesis of 4,5,6-triaryl-3,4-dihydropyrimidin-2(1H)-one and mechanistic study

(Chemical Equation Presented) An efficient one-pot synthesis of 4,5,6-triaryl-3,4-dihydropyrimidin-2(1H)-ones via a three-component Biginelli-type condensation of aldehyde, 2-phenylacetophenone, and urea/thiourea in the presence of a catalytic amount of t-BuOK (20 mol %) is described. The reactions proceeded efficiently at 70 °C to afford the desired products in moderate to good yields. Detailed mechanistic study shows that the Biginelli-type reaction using urea and thiourea proceeds through two totally different pathways. Enone 5 and bis-urea 8 were highly suggested as respective reaction intermediates for reactions involving thiourea and urea as substrates.