55749-30-9Relevant articles and documents
Regioselective reaction: Synthesis of novel Mannich bases derived from 3-(4,6-disubstituted-2-thiomethylpyrimidyl)-4-amino-5-mercapto-1,2-4-triazoles and their antimicrobial properties
Lingappa,Girisha,Kalluraya, Balakrishna,Satheesh Rai,Kumari, Nalilu Suchetha
body text, p. 1858 - 1864 (2009/05/26)
A new series of 3-(4,6-disubstituted-2-thiomethylpyrimidyl)-4-amino-5- mercapto-1,2-4-triazoles have been synthesized. These triazoles on reaction with aldehydes in the presence of acid catalyst forms Schiff's bases. These Schiff's bases can exist both in the thiol as well as in the thione tautomeric form. However when these compounds are subjected to Mannich reaction, M-Mannicli bases 7a-f are obtained rather than the S-Mannich bases. The structures of the new compounds have been confirmed by spectral and analytical data. Few of these Mannich bases have been evaluated for their possible antifungal and antibacterial activity. Most of the tested compounds show significant antifungal and antibacterial activity.
Synthesis of N-substituted 3-nitrophthalimides
Zav'yalov,Dorofeeva,Rumyantseva,Kulikova,Ezhova,Kravchenko,Zavozin
, p. 154 - 156 (2007/10/03)
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