62501-45-5

Basic information

• Product Name: 4,6-dimethyl-1H-pyrimidine-2-thione hydrochloride
• Synonyms: 4,6-Dimethyl-1H-pyrimidine-2-thione hydrochloride;Einecs 248-883-3;4,6-dimethyl-2-mercaptopyrimidine hydrochloride
• CAS NO: 62501-45-5
• Molecular Formula: C₆H₉N₂S*Cl
• Molecular Weight: 176.67
• EINECS: 263-578-5
• Mol File: 62501-45-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 212.9 °C at 760 mmHg
• Flash Point: 82.5 °C
• Appearance: /
• Vapor Pressure: 0.169mmHg at 25°C
• CAS DataBase Reference: 4,6-dimethyl-1H-pyrimidine-2-thione hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-dimethyl-1H-pyrimidine-2-thione hydrochloride(62501-45-5)
• EPA Substance Registry System: 4,6-dimethyl-1H-pyrimidine-2-thione hydrochloride(62501-45-5)

Safety Data

• Hazardous Substances Data: 62501-45-5(Hazardous Substances Data)

Usage

General Description

4,6-Dimethyl-1H-pyrimidine-2-thione hydrochloride is a chemical compound used in the synthesis of pharmaceuticals and other organic compounds. It is a derivative of pyrimidine, a heterocyclic organic compound that is commonly found in nucleic acids and has various biological activities. The addition of the hydrochloride group to the 4,6-dimethyl-1H-pyrimidine-2-thione molecule allows for increased solubility in water and improved stability. 4,6-Dimethyl-1H-pyrimidine-2-thione hydrochloride is used in the pharmaceutical industry for the development of drugs targeting various diseases and disorders, and its versatile properties make it an important building block in organic chemistry research.

InChI:InChI=1/C6H8N2S.ClH/c1-4-3-5(2)8-6(9)7-4;/h3H,1-2H3,(H,7,8,9);1H

Upstream product

• 34248-12-9 trichlorooxobis(triphenylphosphine)rhenium(V) 
• 22325-27-5 4,6-dimethyl-pyrimidine-2-thione 
• 30680-61-6 pyrimidine hydrochloride 
• 123-54-6 acetylacetone 
• 17356-08-0 thiourea 

Downstream Products

• 74537-77-2 2-(4,6-dimethylpyrimidin-2-yl)sulfanylacetamid 
• 298218-02-7 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-N-(3-nitrophenyl)acetamide 
• 22325-27-5 4,6-dimethyl-2-meraptopyrimidine 
• 14001-64-0 4,6-dimethyl-2-methylsulfanyl-pyrimidine 
• 16490-02-1 pyrimidine-4,6-dicarboxylic acid 
• 14161-42-3 4,6-dimethylpyrimidine 1-oxide 
• 98198-62-0 4-(chloromethyl)-6-methylpyrimidine 
• 55749-30-9 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetic acid 
• 3789-54-6 (6R)-3-(4,6-dimethyl-pyrimidin-2-ylsulfanylmethyl)-8-oxo-7t-(2-phenyl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 

Relevant articles and documents

Tris(4,6-dimethylpyrimidine-2-thiolato-N,S)cobalt(III) Monohydrate: a Complex with Three Stable Four-Membered N,S-Chelate Rings

In the title compound, *H2O, the CoIII ion is surrounded by three thiolate S atoms and three azomethine N atoms which define a fac-octahedral geometry that is highly distorted owing to the presence of three four-membered N,S-chelate rings.All three bidentate ligands are planar to within +/-0.06 Angstroem and display bond lengths and angles very close to expected values.Intermolecular hydrogen bonding between the water O atom and an uncoordinated pyrimidine N atom stabilizes the molecular packing.

Novel 2-alkoxy- and 2-alkylthio-substituted pyrimidines containing 2-(1-methyl-1H-pyrrol-2-yl)vinyl moieties: optical and electrochemical properties

A series of novel Y-shaped dyes bearing the D–π–A–π–D fragment comprising central 2-alkoxy-or 2-alkylthio-substituted pyrimidine core and terminal 2-(1-methyl-1H-pyrrol-2-yl)vinyl moieties have been synthesized and studied as potential materials for the organic electronics. The obtained compounds demonstrated an efficient absorption at ～410 nm with the high molar absorption coefficient (29790–40620 dm3 mol?1 cm?1) and fluorescence emission at ～480 nm (ΦF ～ 7.5–8.6%). Thin films of 2-ethyloxy- or 2-ethylthiopyrimidines exhibited the red-shifted photoluminescence (～600 nm).

Structures and chemical equilibria of some N-heterocycles containing amide linkages

Structures and chemical equilibria of 5-carboxy-2-thiouracil (1), 5,6-diphenyl-3-hydroxy-1,2,4-triazine (2), 1-phenyl-3-methyl-5-pyrazolone (3) and 2-mercapto-4,6-dimethylpyrimidine hydrochloride (4) are reported. Their electronic transitions are assigned and pK values are evaluated and discussed.