55750-49-7

Basic information

• Product Name: Ethyl 2,5-Dioxopyrrole-1-carboxylate
• Synonyms: Ethyl 2,5-Dioxopyrrole-1-carboxylate;1H-Pyrrole-1-carboxylic acid, 2,5-dihydro-2,5-dioxo-, ethyl ester;N-Ethyoxycarbonyl MaleiMide;N-Ethoxycarbonylmaleimide;ethyl 2,5-dioxo-2H-pyrrole-1(5H)-carboxylate;N-Carbethoxymaleimide;NSC 266054;Ethyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate
• CAS NO: 55750-49-7
• Molecular Formula: C₇H₇NO₄
• Molecular Weight: 169
• Product Categories: Life Science Chemical Reagents
• Mol File: 55750-49-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 257.3°Cat760mmHg
• Flash Point: 109.4°C
• Appearance: /
• Density: 1.407g/cm³
• Vapor Pressure: 0.0147mmHg at 25°C
• Refractive Index: 1.535
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -3.11±0.20(Predicted)
• CAS DataBase Reference: Ethyl 2,5-Dioxopyrrole-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2,5-Dioxopyrrole-1-carboxylate(55750-49-7)
• EPA Substance Registry System: Ethyl 2,5-Dioxopyrrole-1-carboxylate(55750-49-7)

Safety Data

• Hazardous Substances Data: 55750-49-7(Hazardous Substances Data)

Usage

General Description

Ethyl 2,5-dioxopyrrole-1-carboxylate (EDPC) is a chemical compound with the molecular formula C8H7NO4 and a molecular weight of 181.14 g/mol. It belongs to the chemical class of pyrroles, which are heterocyclic aromatic organic compounds composed of a five-membered ring with four carbon atoms and one nitrogen atom. The physical properties of EDPC include a strong, musty odour and a colorless to light yellow appearance. It is used in various chemical reactions due to its reactive nature. Despite its usefulness in chemical synthesis, EDPC can be hazardous when improperly handled, posing risks to the skin, eyes, and respiratory system. It is, therefore, essential to follow proper handling procedures when using this chemical.

InChI:InChI=1/C7H7NO4/c1-2-12-7(11)8-5(9)3-4-6(8)10/h3-4H,2H2,1H3

Upstream product

• 541-59-3 maleiimide 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 192212-24-1 tert-butyl 5-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentylcarbamate 
• 124529-64-2 tert-butyl (6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl)carbamate 
• 139112-38-2 1,1',1''-(nitrilotris(ethane-2,1-diyl))tris(1H-pyrrole-2,5-dione) 
• 209395-32-4 N-propargylmaleimide 
• 34321-81-8 1-(2-(2-hydroxyethoxy)ethyl)-1H-pyrrole-2,5-dione 
• 134272-63-2 N-[2-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-ethyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

Inactivation method

The present invention relates to the field of thermostable enzymes, methods for their inactivation, and related uses, kits and reagents. In particular, the invention relates to a method for reversible inactivation of thermophilic enzymes by chemical modification under aqueous or non-aqueous conditions.

Dendrimer-like polymeric DNAs as chemiluminescence probes for amplified detection of telomere DNA on a solid-phase membrane

For the first time, an amplified chemiluminescence (CL) detection of the telomere DNA spotted on a nylon membrane is described here, based on the direct hybridization with the CL probe of dendrimer-like polymeric DNAs possessing a large number of guanine moieties. This probe was synthesized by sense and antisense hybridization between Y-shaped DNAs and then could hybridize with the target DNA. The Royal Society of Chemistry.

Preparation and some properties of maleimido acids and maleoyl derivatives of peptides.

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