55771-10-3

Upstream product

• 64-17-5 ethanol 
• 504-02-9 1,3-cylohexanedione 
• 100-52-7 benzaldehyde 

Downstream Products

• 138884-16-9 8-phenyl-7,8,9,10,11,12-hexahydrobenzo-4,7-phenanthrolin-9-one 
• 95200-84-3 9-phenyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione 

Relevant academic research and scientific papers

Application of SiO 2 nanoparticles as an efficient catalyst to develop syntheses of perimidines and tetraketones

Abstract: In this paper, we explore the catalytic activity of SiO 2 nanoparticles (NPs) as an eco-friendly, efficient and reusable catalyst in the synthesis of 2,3-dihydro-1H-perimidines as well as tetraketones. For tetraketones syntheses, a si

Merging supramolecular catalysis and aminocatalysis: Amino-appended β-cyclodextrins (ACDs) as efficient and recyclable supramolecular catalysts for the synthesis of tetraketones

Well-designed amino-appended β-cyclodextrins (ACDs) with an amino side chain of different lengths at the primary face of β-CD were synthesized and employed in the catalytic synthesis of a series of tetraketones as supramolecular catalysts in water for the first time. Yields of 58-97% were obtained with up to 30 examples of substrate. The catalyst could be recycled easily, while a 92% yield and 84% rate of catalyst recovery could be achieved after 8 cycles of catalyst recycling. Moreover, a catalytic mechanism merging supramolecular catalysis and aminocatalysis could be proposed through detailed 1D and 2D NMR, ESI-MS and Job plot analyses. This protocol retained the promising characteristics of ambient temperature, green medium, simple operation, broad substrate scope, excellent yields, superb catalyst recycling performance and unique catalytic mechanism.

Alkaline earth metal catalyzed, one-pot, multi-component approach for the synthesis of dihydropyridine, acridine and xanthene derivatives in water

Ca(II) catalyzed one-pot multicomponent approach for the biologically important diverse heterocyclic compounds such as hexahydroxanthene diones, dihydropyridines and octahydroacridine diones has been described in water. Use of environmentally benign catal

CsF mediated rapid condensation of 1,3-cyclohexadione with aromatic aldehydes: Comparative study of conventional heating vs. ambient temperature

A mild, efficient and high yielding protocol for the synthesis of 2,2′-arylmethelene dicyclohexane-1,3-dione derivatives at room temperature and 9-aryl-1,8-dihydrooctahydroxanthene at conventional heating using cesium fluoride as a catalyst is reported. T

An efficient and simple synthesis of tetraketones catalyzed by Yb(OTf) 3-sio2 under solvent free conditions

A novel and efficient three-component one-pot condensation method has been described for the synthesis of tetraketones or arylmethylene[bis(3-hydroxy-2- cyclohexene-1-ones)] using Yb(OTf)3-SiO2 and amine as catalytic system under sol

Synthesis of tetraketones in water and under catalyst-free conditions

A simple, environmentally friendly, tandem Knoevenagel condensation and Michael addition procedure is reported. The reactions between cyclic-13-diketones and a variety of aldehydes were carried out in water to afford tetraketones (64-99%). In this green synthetic protocol, the solvent water itself catalysed the reaction by hydrogen bonding, thus avoiding the use of any other catalysts to make the work up procedure easier.

Tetraketones: A new class of tyrosinase inhibitors

Twenty-eight tetraketones (1-28) with variable substituents at C-7 were synthesized and evaluated as tyrosinase inhibitors. Remarkably compounds 25 (IC50 = 2.06 μM), 11 (IC50 = 2.09 μM), 15 (IC 50 = 2.61 μM), and 27 (ICsu

New methods of synthesis of 1,2,3,4,5,6-hexahydrobenzo[A][4,7]phenanthrolin-4-ones

New methods of synthesis of 5-aryl(heteryl)-1,2,3,4,5,6-hexahydrobenzo[a][4,7]phenanthrolin-4-ones have been developed on the basis of the reaction of 1,3-cyclohexanedione with Schiff bases derived from 6-aminoquinolines, as well as of the three-component

Synthesis of Aza- and Diazaphenanthrene Derivatives by Condensation of Schiff Bases with Cyclic β-Diketones

Condensation of 1,3-cyclohexanedione and 1,3-indandione with Schiff bases derived from 2-naphthyl- and 6-quinolylamine gave new aza- and diazaphenanthrene derivatives containing fused cyclohexene and indenone rings. The reactions were carried out by heati

9-(2-methylphenyl)-3,4,5,6,9,10-hexahydroxanthene-1,8(2H,7H)-dione

Several 9-(2-R phenyl)xanthenediones have been synthesized and the x-ray diffraction structure for the 2-methylphenyl derivative (4b) has been determined. This compound crystallizes in the monoclinic system, space group P21/n, with a = 11.729 (