557757-32-1

Usage

InChI:InChI=1/C8H9BrO3/c1-11-7-4-6(10)8(12-2)3-5(7)9/h3-4,10H,1-2H3

Upstream product

• 31558-41-5 4-bromo-2,5-dimethoxybenzaldehyde 
• 93-02-7 2,5-dimethoxybenzaldehyde 
• 376396-10-0 4-bromo-6,6-dimethoxy-2,4-cyclohexadien-1-one 
• 151-10-0 1,3-Dimethoxybenzene 
• 7368-78-7 4-bromoguaiacol 

Downstream Products

• 1450994-71-4 (4-bromo-2,5-dimethoxyphenoxy)(tert-butyl)dimethylsilane 
• 1450994-72-5 tert-butyl(2,5-dimethoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)dimethylsilane 
• 557757-36-5 [2,5-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-[5,8-bis-(2-methoxy-ethoxymethoxy)-2,2-dimethyl-2H-chromen-6-yl]-methanone 
• 557757-35-4 [2,5-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-[5,8-bis-(2-methoxy-ethoxymethoxy)-2,2-dimethyl-2H-chromen-6-yl]-methanol 
• 557757-37-6 [2,5-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-(5,8-dihydroxy-2,2-dimethyl-2H-chromen-6-yl)-methanone 
• 557757-38-7 6-[2,5-bis-(tert-butyl-dimethyl-silanyloxy)-benzoyl]-2,2-dimethyl-2H-chromene-5,8-dione 
• 557757-30-9 6-(2,5-dihydroxy-benzoyl)-2,2-dimethyl-2H-chromene-5,8-dione 
• 557757-33-2 1-bromo-4-(1,1-dimethyl-prop-2-ynyloxy)-2,5-dimethoxy-benzene 

Relevant academic research and scientific papers

Lewis Acid-Mediated Site-Selective Synthesis of Oxygenated Biaryls from Methoxyphenols and Electron-Rich Arenes

A rapid, efficient, and metal-free Lewis acid-mediated methodology has been developed for the site-selective synthesis of unsymmetrical oxygenated biaryls. This simple and efficient methodology furnished highly oxygenated and functionalized unsymmetrical biaryls in good to excellent yields by the direct oxidative coupling of electron-rich arenes to the α-position of carbonyl functionality of in situ generated masked benzoquinones.

Total synthesis of eryvarin H and its derivatives and their biological activity as ERRγ inverse agonist

Total synthesis of eryvarin H and a biological investigation of its analogues as a potential inverse agonist of ERRγ are described here. Among the 13 analogues prepared by the modular synthetic route, eryvarin H and compound 12 showed meaningful ERRγ inverse agonistic activities along with moderate selectivity over ERα and other nuclear receptors in the cell-based reporter gene assay.

Total synthesis of atroviridin

A total synthesis of atroviridin (1) based on biosynthetic principles is presented. The tetracyclic xanthone structure of the natural product was constructed by coupling aryl bromide 8 with aldehyde 7 and subsequent intramolecular conjugate addition on a quinone precursor. Bromide 8 was produced from aldehyde 9 via a sequence of steps involving Baeyer-Villiger oxidation and Claisen cyclization.