557771-62-7Relevant articles and documents
Stereoselective and Divergent Aza-Adenosine and Aza-Guanosine Syntheses from Xylofuranose, the Key Fragments of a STING Cyclic Dinucleotide Agonist
Eastgate, Martin,Ortiz, Adrian,Rogers, Amanda,Schmidt, Michael A.,Xu, Zhongmin,Yuan, Changxia,Zhu, Jason
supporting information, (2021/07/31)
The stereoselective and divergent synthesis of two aza-nucleosides is reported. Starting from xylofuranose 9, aza-adenosine 2 was prepared in 13 steps and 7% overall yield, and aza-guanosine 3 was prepared in 13 steps and 7.8% overall yield. Compared to t