55779-18-5 Usage
Chemical Properties
Pale Yellow Solid
Originator
Arprinocid,NANJING PHARMA
Uses
Arprinocide can be used as a Coccidiostat used in veterinary medicine.
Manufacturing Process
To a solution of potassium t-butoxide in absolute ethanol slowly adding dry
adenine. This mixture was stirred for about 2 h, and then 2-chloro-6-
fluorobenzyl chloride was added over a period of about 4 h. The resulting
mixture was heated to reflux with stirring and allowed to react for about 42 h,
after which it was cooled to about 10°C. The crude product thus formed was
isolated by filtration and then washed with ice cold ethanol and ice cold water
to yield a 6-amino-9-(2-chloro-6-fluorobenzyl)purine.
Brand name
Arpocox (Merck).
Synthesis Reference(s)
The Journal of Organic Chemistry, 43, p. 960, 1978 DOI: 10.1021/jo00399a034
Check Digit Verification of cas no
The CAS Registry Mumber 55779-18-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,7,7 and 9 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 55779-18:
(7*5)+(6*5)+(5*7)+(4*7)+(3*9)+(2*1)+(1*8)=165
165 % 10 = 5
So 55779-18-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H9ClFN5/c13-8-2-1-3-9(14)7(8)4-19-6-18-10-11(15)16-5-17-12(10)19/h1-3,5-6H,4H2,(H2,15,16,17)
55779-18-5Relevant articles and documents
Specific Dealkylation of 3-Benzyladenines in the Presence of 9-Benzyladenines
Weinstock, Leonard M.,Tull, Roger J.,Douglas, Alan W.,Shinkai, Ichiro
, p. 5419 - 5421 (1980)
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Process for formulating a synthetic drug for use in animal feed, and resulting formulation
-
, (2008/06/13)
A method of formulating a synthetic drug for use in animal feed, for the purpose of reducing carry-over of the synthetic drug to subsequent lots of animal feed in the feed mill.
Phase-Transfer Catalysis in the N-Benzylation of Adenine
Shinkai, I.,Zwan, M. C. Vander,Hartner, F. W.,Reamer, R. A.,Tull, R. J.,Weinstock, L. M.
, p. 197 - 198 (2007/10/02)
A convenient phase-transfer catalysis in the N-benzylation of adenine is described.The benzylation of adenine with benzyl halides in a two-phase system containing phase-transfer catalyst gave 9-benzylated adenines as a major product accompanied with 3-benzylated adenines.
