557798-56-8

Basic information

• Product Name: methyl 2-bromo-2-(3,4-difluorophenyl)acetate
• Synonyms: methyl 2-bromo-2-(3,4-difluorophenyl)acetate
• CAS NO: 557798-56-8
• Molecular Weight: 265.054
• Mol File: 557798-56-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: methyl 2-bromo-2-(3,4-difluorophenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-bromo-2-(3,4-difluorophenyl)acetate(557798-56-8)
• EPA Substance Registry System: methyl 2-bromo-2-(3,4-difluorophenyl)acetate(557798-56-8)

Safety Data

• Hazardous Substances Data: 557798-56-8(Hazardous Substances Data)

Upstream product

• 658-93-5 (3,4-difluorophenyl)acetic acid 
• 210530-71-5 (3,4-difluoro-phenyl)-acetic acid methyl ester 
• 67-56-1 methanol 

Downstream Products

• 741682-96-2 methyl 2-(3,4-difluorophenyl)-2-(2H-1,2,3,4-tetrazol-2-yl)acetate 
• 1170298-33-5 C₁₃H₁₅F₂NO₂ 
• 1170298-25-5 methyl 2-(3,4-difluorophenyl)-2-(1H-pyrazol-1-yl)acetate 
• 1170298-27-7 C₁₁H₉F₂N₃O₂ 
• 1170298-30-2 C₁₁H₉F₂N₃O₂ 
• 1170298-31-3 C₁₀H₈F₂N₄O₂ 
• 741682-94-0 methyl 2-(3,4-difluorophenyl)-2-(2-oxo-1(2H)pyridinyl)acetate 
• 1196960-55-0 C₁₄H₁₆F₂N₂O₅S 
• 1196960-56-1 C₁₈H₂₂F₂N₂O₅ 

Relevant articles and documents

PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST

Disclosed herein is a pyrazolotriazolopyrimidine derivative or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof useful as A2A receptor antagonist, and a pharmaceutical composition comprising the same. Also disclosed herein is a method of treating cancer using the pyrazolotriazolopyrimidine derivative or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof as A2A receptor antagonist.

Identification and characterization of a selective radioligand for melanin-concentrating hormone 1-receptor (MCH1R)

We have developed and characterized [35S]4a as a potent and selective radioligand for melanin-concentrating hormone 1-receptor (MCH1R). Compound [35S]4a showed appreciable specific signals in brain slices prepared from wild-type mice

MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS CONTAINING PIPERIDINE DERIVATIVES AS THE ACTIVE INGREDIENT

The invention provides melanin-concentrating hormone receptor antagonists containing as the active ingredient piperidine derivatives represented by the general formula [I]: ???[wherein R1 is hydrogen, hydroxyl, lower alkyl, or the like; R2, R3a, R3b, R4a, R4b, R5a, R5b and R6 each stands for hydrogen, halogen, or the like; W1 and W2 each independently stands for -O-, -CH2-, or the like; Y1, Y2, Y3 and Y4 stand for -CH-, -CF-, -N-, or the like; Z stands for lower alkyl, an aliphatic heterocyclic group, or the like; Ar is a mono- or bi-cyclic aliphatic heterocycle or an aromatic heterocycle; and n is an integer of 1 to 8]. The compounds act as antagonist against melanin-concentrating hormone receptor and are useful as drugs for central diseases, circulatory diseases, or metabolic diseases.