55790-39-1

Usage

InChI:InChI=1/C7H17NS/c1-3-8(4-2)6-5-7-9/h9H,3-7H2,1-2H3

Upstream product

• 622-93-5 3-diethylamino-propan-1-ol 
• 17356-08-0 thiourea 
• 104-77-8 3-diethylaminopropyl chloride 
• 13012-54-9 thioacetic acid S-(3-chloropropyl) ester 
• 109-89-7 diethylamine 

Downstream Products

• 107778-91-6 thiobenzoic acid S-(3-diethylamino-propyl ester) 
• 122680-00-6 diethyl-methyl-[3-(3-oxo-1,3-diphenyl-propylsulfanyl)-propyl]-ammonium; iodide 

Relevant academic research and scientific papers

Design, synthesis and biological evaluation of novel podophyllotoxin derivatives bearing 4β-disulfide/trisulfide bond as cytotoxic agents

A novel series of C-4β-disulfide/trisulfide-containing podophyllotoxin derivatives were designed, synthesized, and biologically evaluated for their cytotoxic activities against human cancer cell lines, including KB (Mouth Epidermal Carcinoma Cells) and KB/VCR (Vincristine-resistant Mouth Epidermal Carcinoma Cells). Most of these compounds exhibited promising moderate to good cytotoxic activities. In particular, some of them displayed even superior activities to that of etoposide, especially for KB/VCR cell lines, indicating that introduction of the disulfide/trisulfide moiety would be beneficial for overcoming the multi-drug resistant limitation of etoposide. Moreover, the metabolic evaluation of the most promising compound was further performed to reveal that disulfide bond can be stable in human plasma over 8 hours, indicating good potential of these compounds for in vivo anti-cancer activities.

Modified ion exchange resins and use thereof

A modified strongly acidic ion exchange resin of a sulfonic acid type is disclosed. Modification is conducted by ionically binding a particular N,N-di-substituted mercaptoalkylamine to a strongly acidic ion exchange resin of a sulfonic acid type. The N,N-di-substituted mercaptoalkylamine is specifically represented by the following formulae: STR1 wherein R1 represents hydrogen or a C1-6 alkyl group, R2 and R3 independently represent a C1-10 alkyl group, a and b denote 0-3, respectively, a+b denotes 2 or 3, and m denotes 4 or 5. The modified ion exchange resin makes an improved catalyst in the preparation of a bisphenol by the condensation reaction of a phenol with a ketone.

Omega-quaternary ammonium alkyl esters and thioesters of acidic nonsteroidal antiinflammatory drugs

Quaternary ammonium alkyl esters and thioesters of acidic nonsteroidal anti-inflammatory drugs (NSAIDs) are disclosed. These esters and thioesters display the anti--inflammatory profile of the parent NSAIDs with greatly reduced gastrointestinal irritancy, providing a more favorable separation of therapeutic activity and toxicological side effects than the parent NSAIDs.