55805-25-9

Usage

Uses

Used in Pharmaceutical Industry:
(4-(1,1-difluoroethyl)phenyl)methanol is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
(4-(1,1-difluoroethyl)phenyl)methanol is used as a building block for the synthesis of various agrochemicals, aiding in the creation of new pesticides and other agricultural products.
Used in Organic Synthesis:
(4-(1,1-difluoroethyl)phenyl)methanol is used as a reagent in organic synthesis, enabling the production of a wide range of chemical compounds for various applications.
Used in Chemical Research:
(4-(1,1-difluoroethyl)phenyl)methanol is used as a research chemical, facilitating the study and understanding of chemical reactions and processes.
Safety Precautions:
It is important to handle (4-(1,1-difluoroethyl)phenyl)methanol with care as it may be hazardous if not handled properly. Protective equipment should be worn when working with this chemical to ensure safety.

Upstream product

• 444915-84-8 methyl 4-(1,1-difluoroethyl)benzoate 
• 790601-53-5 [4-(1,1-difluoroethyl)phenyl]methanamine 
• 3609-53-8 methyl 4-acetylbenzoate 
• 55805-14-6 4-(1,1-difluoroethyl)benzoic acid 

Downstream Products

• 55805-22-6 4-(1,1-difluoroethyl)benzaldehyde 

Relevant academic research and scientific papers

COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES

The present disclosure relates to compounds according to Formulae (I), (II) and (VIII), useful for treating diseases.

Gem-difluoro ethyl substitutional diphenylethene and diphenylethane derivative as well as preparation method and application thereof

The invention discloses gem-difluoro ethyl substitutional diphenylethene and diphenylethene diphenylethane derivatives as well as a preparation method and application thereof. A 4' bit of a B aromatic ring of diphenylethane/diphenylethene is subjected to chemical structure modification through gem-difluoro ethyl, and meanwhile, a 2' bit is modified into nitro or an amino group and other substituent groups; the gem-difluoro ethyl substitutional diphenylethene and diphenylethane derivative has relatively high antitumor activity in vitro, and the antitumor activity of a trans-form is better than the antitumor activity of a cis-form; with the introduction of fluorine atoms, not only is the physical property of the compound changed, but also the antitumor activity in vitro is improved at the same time, and the derivative has a relatively good inhibiting effect on multiple tumor cells.

BICYCLIC AZAHETEROCYCLIC COMPOUNDS AS NR2B NMDA RECEPTOR ANTAGONISTS

Disclosed are chemical entities of Formula (I): wherein R1 and Z are defined herein, as NR2B subtype selective receptor antagonists. Also disclosed are pharmaceutical compositions comprising a chemical entity of Formula (I), and methods of treating various diseases and disorders associated with NR2B antagonism, e.g., diseases and disorders of the CNS, such as depression, by administering a chemical entity of Formula (I).

BENZIMIDAZOLYL-METHYL UREA DERIVATIVES AS ALX RECEPTOR AGONISTS

The present invention relates to benzimidazolyl-methyl urea derivatives of formula (I), wherein n, D, E, R1, R2, R3, R4, R6, R7, R8 and R9 are as defined in the description, their preparation and their use as pharmaceutically active compounds.

FLUOROISOQUINOLINE SUBSTITUTED THIAZOLE COMPOUNDS AND METHODS OF USE

The invention relates to thiazole compounds of Formula (I) and compositions thereof useful for treating diseases mediated by protein kinase B (PKB) where the variables have the definitions provided herein. The invention also relates to the therapeutic use of such thiazole compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.

Process for producing fluorinated organic compounds containing a difluoromethylene group from compounds comprising at least one carbonyl function

A novel process for producing fluorinated organic compounds containing a difluoromethylene group, essentially characterized by reacting organic compounds containing a carbonyl function with molybdenum hexafluoride at room temperature and under atmospheric