55814-41-0 Usage
Uses
Different sources of media describe the Uses of 55814-41-0 differently. You can refer to the following data:
1. Mepronil is an benzanilide based fungicide found in the raw materials of herbal medicine.
2. Mepronil is used to control Basidiomycetes diseases in rice,
cereals, potatoes, vegetables, sugar beet, fruit, vines, tobacco, turf grass
and other crops.
Definition
ChEBI: A member of the class of benzamides, obtained by formal condensation of the carboxy group of 2-methylbenzoic acid with the amino group of 3-(ispropyloxy)aniline. A fungicide used to control diseases caused by Basidomycetes including Rhizoctonia
Metabolic pathway
Mepronil is an analogue of flutolanil containing a 2-methyl group as
opposed to the 2-trifluoromethyl group. The compounds have the same
mode of action and are metabolised via similar routes except that the
methyl group of mepronil provides an extra site for metabolic attack.
The compound is metabolised by dealkylation and hydroxylation at
both the methyl and isopropyl groups and by aryl hydroxylation. Some
hydrolysis occurs in plants and animals.
Degradation
Mepronil is stable to light, heat and air and in solution over a pH range of
3-10. It is hydrolysed under strongly alkaline conditions (PM). Mepronil
on a silica gel surface exposed to sunlight between September and
December (Japan) was 66% degraded with an estimated half-life of 36
days. This could be shortened by the addition of the photosensitiser xanthone
(Yumita and Yamamoto, 1982). Irradiation of an aqueous solution
with UV light at 30 °C afforded 32% degradation in 80 hours. 14C-Aniline
and 14C-carbonyl labelling was used in these experiments. Carbonyl label
afforded marpally more metabolites, indicating that some amide bond
cleavage occurred. Twelve photo-products were identified and four
unknowns were detected. Aqueous photolysis afforded somewhat fewer
products than the surface irradiation. Hydroxylation occurred initially at
four positions in the molecule and these were followed by further oxidation,
hydrolysis, cyclisation or cleavage. The products are shown in
Scheme 1. The major products (5-10%) of surface photolysis were compounds
2, 3 and 4 and on aqueous photolysis were 6 and 13 with an
unknown derived only from carbonyl labelling.
Check Digit Verification of cas no
The CAS Registry Mumber 55814-41-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,8,1 and 4 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 55814-41:
(7*5)+(6*5)+(5*8)+(4*1)+(3*4)+(2*4)+(1*1)=130
130 % 10 = 0
So 55814-41-0 is a valid CAS Registry Number.
InChI:InChI=1/C17H19NO2/c1-12(2)20-15-9-6-8-14(11-15)18-17(19)16-10-5-4-7-13(16)3/h4-12H,1-3H3,(H,18,19)
55814-41-0Relevant articles and documents
Direct Amidation of Carboxylic Acids with Nitroarenes
Wang, Shao-Peng,Cheung, Chi Wai,Ma, Jun-An
, p. 13922 - 13934 (2019/11/03)
N-Aryl amides are an important class of compounds in pharmaceutical and agrochemical chemistry. Rapid and low-cost synthesis of N-aryl amides remains in high demand. Herein, we disclose an operationally simple process to access N-aryl amides directly from readily available nitroarenes and carboxylic acids as coupling substrates. This method involves the in situ activation of carboxylic acids to acyloxyphosphonium salt for one-pot amidation, without the need for isolation of the corresponding synthetic intermediates. Furthermore, the ease of preparation and workup allow the quick and efficient synthesis of a wide range of N-aryl amides, including several amide-based druglike and agrochemical molecules.
Process for producing 2-alkylbenzanilide
-
, (2008/06/13)
2-Alkylbenzanilide is produced by reacting an alkyl 2-alkylbenzoate having the formula STR1 wherein X represents a lower alkyl group and R represents a lower alkyl group with an aniline having the formula STR2 wherein Y represents hydrogen atom, an alkoxy